ReviewAmerican journal of hematology2025
Addressing Anemia in High-Altitude Populations: Global Impact, Prevalence, Challenges, and Potential Solutions.
Review in American journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Altitude thresholds for hemoglobin and plasma volume regulation in adult residents of different altitudes and their impact on hemoglobin concentration.Physiological reports · 2026Article
- Anemia and hemoglobin thresholds of 12.5 and 13.0 g/dL are associated with distinct cardiovascular and all-cause mortality risks in COPD.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Observational
- Anemia crisis among children in Peru: a scoping review.Revista panamericana de salud publica = Pan American journal of public health · 2026Review
- Addressing Anemia in High-Altitude Populations: Global Impact, Prevalence, Challenges, and Potential Solutions.American journal of hematology · 2025Review
- The New WHO Cut-off Point for Defining High-altitude Anemia may be Inadequate.Inquiry : a journal of medical care organization, provision and financingArticle
- High-altitude exposure and ischemic stroke: pathophysiological mechanisms and current perspectives.Frontiers in neurologyReview
- Beyond deficiency: The emerging health risks of excess iron.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Anemia, a global health challenge affecting a quarter of the global population, results from diverse causes such as nutritional deficiencies, chronic diseases, and genetic factors. It disproportionately impacts women of reproductive age and children, leading to significant morbidity and mortality. While high-altitude populations face unique diagnostic challenges due to natural hemoglobin increases, the current World Health Organization cutoffs often overestimate anemia in these regions. Altitude corrections significantly alter prevalence rates, particularly in South American children, leading to misdiagnosis. Proposed solutions include population-specific thresholds and iron status markers like serum hepcidin, though economic constraints and limited test availability remain challenges. Tailored strategies informed by genetic research highlight adaptations in Tibetan and Ethiopian highlanders, demonstrating the need for region-specific approaches. Socioeconomic factors exacerbate anemia in high-altitude areas. Addressing anemia requires updated diagnostic criteria, personalized strategies, and increased awareness to ensure accurate assessments and interventions in diverse populations, especially those residing at high altitudes.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.