Evidence map›Paper›PMID 40600721›Full record

ArticleMicrobiology spectrum2025

Design, development, and validation of new fluorescent strains for studying oral streptococci.

Daniel I Peters, Iris J Shin, Alyssa N Deever, Justin R Kaspar

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Daniel I PetersDivision of Biosciences, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID 0009-0005-5608-1289
Iris J ShinDivision of Biosciences, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID 0009-0009-6754-1307
Alyssa N DeeverDivision of Biosciences, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID 0009-0001-9003-0160
Justin R KasparDivision of Biosciences, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID 0000-0001-6901-5524

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Interactions of Streptococcus mutans in Supragingival BiofilmsR03DE031766 · NIDCR · OHIO STATE UNIVERSITY · PI KASPAR, JUSTIN RAY · 2022 to 2023
$315k
NCI NIH HHS P30 CA016058NIDCR NIH HHS R03 DE031766NIDCR NIH HHS R03DE031766
6 · The paper itself

Abstract

Bacterial strains that are genetically engineered to constitutively produce fluorescent proteins have aided our study of bacterial physiology, biofilm formation, and interspecies interactions. Here, we report on the construction and utilization of new strains that produce the blue fluorescent protein mTagBFP2, the green fluorescent protein sfGFP, and the red fluorescent protein mScarlet-I3 in species

Indexed as

Luminescent ProteinsMouthStreptococcusBiofilmsGreen Fluorescent ProteinsHumansMicroscopy, ConfocalRed Fluorescent ProteinStreptococcus gordoniiStreptococcus mutansStreptococcus sanguisGreen Fluorescent ProteinsLuminescent ProteinsRed Fluorescent Proteinbiofilmconfocal microscopyeDNAfluorescent microscopyoral microbiologysingle-cell analysisStreptococcus

Identifiers

PMID40600721
PMCPMC12323655

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.