Evidence map›Paper›PMID 40603372›Full record

ArticleScientific reports2025

Association between the DASH diet and Alzheimer's disease in a case-control study.

Mohammad Mehdi Abbasi, Sajjad Khandae, Mahshad Shahabi, Mousa Attarzadeh, Mahdiyeh Karimi, Hoora Saghafi, Soodeh Razeghi, Fatemeh Khamseh, Bahram Rashidkhani

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad Mehdi AbbasiStudent Research Committee, Department, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-3179-9527
Sajjad KhandaeStudent Research Committee, Department, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahshad ShahabiStudent Research Committee, Department, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mousa AttarzadehIran Dementia and Alzheimer association, Tehran, Iran.
Mahdiyeh KarimiStudent Research Committee, Department, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hoora SaghafiStudent Research Committee, Department, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Soodeh RazeghiDepartment of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh KhamsehDepartment of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Bahram RashidkhaniDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. rashidkhani@yahoo.com.

Funding

National Nutrition and Food Technology Research Institute IR.SBMU.NNFTRI.REC.1402.027
6 · The paper itself

Abstract

The findings on the connection between Alzheimer's disease and the dietary approaches to stop hypertension (DASH) are inconsistent. Additionally, the relationship between Alzheimer's and the DASH diet has not been explored in the Middle East region. This case-control study aimed to evaluate the association between adherence to DASH diet and the risk of Alzheimer's disease. The study included 212 participants (106 cases and 106 controls). Cases were recruited among people in the early stages of the disease who had been diagnosed with Alzheimer's disease within the past six months. Controls were selected from health centers across Tehran. Dietary intake was assessed using a validated 168-item food frequency questionnaire. Four DASH diet indices (Dixon, Mellen, Fung, and Günther) were used to evaluate the adherence. After adjusting for potential confounders, higher adherence to Günther's, Mellen's, and Fung's DASH diet indices were significantly associated with a reduced risk of Alzheimer's disease (Mellen's OR: 0.29; 95% CI: 0.10-0.83; Fung's OR: 0.22; 95% CI: 0.08-0.65; Günther's OR: 0.36; 95% CI: 0.13-1.00). Adherence to DASH dietary pattern might be associated with a decreased risk of Alzheimer's disease. Future studies should aim to investigate the association in a prospective design in the Middle East.

Indexed as

Alzheimer DiseaseDietary Approaches To Stop HypertensionAgedCase-Control StudiesFemaleHumansIranMaleMiddle AgedRisk FactorsAlzheimerDASHDementiaDietDietary patternNutrition

Identifiers

PMID40603372
PMCPMC12223243

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.