ArticleScientific reports2025
Association between hepatitis A B vaccination and hearing loss across frequencies based on NHANES.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
This study investigates the relationship between hepatitis A and B vaccinations and hearing loss, along with Pure Tone Average (PTA). Data from 5553 U.S. adults aged 20-69 in National Health and Nutrition Examination Survey (NHANES) cycles 2011-2012 and 2015-2016 were analyzed using multivariate regression to assess vaccination status effects on hearing loss and PTA. After adjustment for confounders, ≥ 2 doses of hepatitis A vaccine showed a significant inverse association with speech-frequency hearing loss (OR 0.76, 95% CI 0.60-0.97). ≥ 3 doses of hepatitis B vaccine correlated positively with right ear low-frequency PTA (β 1.22, 95% CI 0.24-2.20). Subgroup analyses indicated that hepatitis A vaccine benefits females and Hispanic individuals, while hepatitis B impacts are more pronounced in non-Hispanic whites, married individuals, and smokers. Mediation analysis excluded antibody mediation in these associations. Adequate hepatitis A vaccination protects against speech-frequency hearing loss, whereas hepatitis B vaccination may increase low-frequency PTA in the right ear. These findings highlight the importance of hearing health monitoring in specific populations and warrant further research into underlying mechanisms.
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