ArticleNature2025
WSTF nuclear autophagy regulates chronic but not acute inflammation.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Canonical and noncanonical autophagy in immunity.Immunity · 2026Review
- A Mechanism-Based Framework for Anti-Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell-Based Interventions.Aging cell · 2026Review
- Intervening in aging and related diseases with gene therapy techniques.Cell reports. Medicine · 2026Review
- Polysaccharide-Based Approaches for Inflammation Treatment: Anti-Inflammatory Mechanisms, Delivery Approaches and Translational Prospects.Biomolecules · 2026Review
- Exploring molecular signatures of senescence with marker, an R Toolkit for evaluating gene sets as phenotypic markers.NAR genomics and bioinformatics · 2026Article
- Therapeutic potential of glycyrrhizic acid in inflammation-related diseases: from HMGB1-oriented molecular insights to preclinical application.Archives of pharmacal research · 2026Review
- Inflammation and wound healing: a comprehensive overview of mechanisms, therapeutic strategies, and translational perspectives.Biomarker research · 2026Review
- The emerging role and therapeutic targeting of autophagy-lysosome pathway in the pathogenesis of Parkinson's disease.Translational neurodegeneration · 2026Review
- Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS inLife science alliance · 2026Article
- Article
- Membrane atg8ylation and autophagy in protection against Mycobacterium tuberculosis.Journal of immunology (Baltimore, Md. : 1950) · 2026Review
- Review
- An anti-inflammatory autophagic target in chronic diseases.Cell research · 2026Article
- Metformin inhibits nuclear egress of chromatin fragments in senescence and aging.Nature aging · 2026Article
- Carrier-Free Supramolecular Hydrogel Self-Assembled from Triterpenoid Saponins from Traditional Chinese Medicine: Preparation, Characterization, and Evaluation of Anti-Inflammatory Activity.Gels (Basel, Switzerland) · 2026Article
- Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling?The EMBO journal · 2025Article
Corrections and comments
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Authors and funding
37 authors.
Yu WangCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Vinay V EapenDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.
Yaosi LiangCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-3478-0864
Athanasios KournoutisAutophagy Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Marc Samuel ShermanDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Yanxin XuCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Angelique OnoratiCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Xianting LiDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xiaoting ZhouDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kathleen E CoreyDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Kuo DuDepartment of Medicine, Duke University, Durham, NC, USA.ORCID 0000-0002-1446-4653
Ana Maria Cabral BurkardCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Chia-Kang HoCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-6861-7870
Jing XieDepartment of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Hui ZhangDepartment of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Raquel Maeso-DíazDepartment of Medicine, Duke University, Durham, NC, USA.
Xinyi MaDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.
Ulrike RieprechtCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0009-0002-9682-3994
Tara O'BrienCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Murat CetinbasDepartment of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Lu WangDepartment of Biochemistry and Structural Biology, Sam and Ann Barshop Institute for Longevity and Aging Studies, UT Health San Antonio, San Antonio, TX, USA.
Jihe LiuBioinformatics Core, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Corey BretzAging, Cancer and Immuno-oncology Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Aaron P HavasAging, Cancer and Immuno-oncology Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID 0000-0003-4291-8015
Zhuo ZhouState Key Laboratory of Common Mechanism Research for Major Diseases, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, China.ORCID 0000-0001-5862-9854
Shannan J Ho SuiBioinformatics Core, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-6191-4709
Srinivas Vinod SaladiDepartment of Cell and Cancer Biology, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA.ORCID 0000-0001-8147-4379
Ruslan I SadreyevDepartment of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Peter D AdamsAging, Cancer and Immuno-oncology Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID 0000-0002-0684-1770
Robert E KingstonDepartment of Molecular Biology and MGH Research Institute, Massachusetts General Hospital, Boston, MA, USA.
Anna Mae DiehlDepartment of Medicine, Duke University, Durham, NC, USA.ORCID 0000-0003-1859-089X
Benjamin AlmanDepartment of Orthopaedic Surgery, Duke University, Durham, NC, USA.ORCID 0000-0002-7302-122X
Wolfram GoesslingDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Zhenyu YueDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-8730-8515
Xiao-Fan WangDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA. xiao.fan.wang@duke.edu.ORCID 0000-0001-7875-3940
Terje JohansenAutophagy Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø, Norway. terje.johansen@uit.no.ORCID 0000-0003-1451-9578
Zhixun DouCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA. zdou@mgh.harvard.edu.ORCID 0000-0002-3069-3907
Funding
The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0MROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6MThe Duke Senescent Cell Evaluations in Normal Tissues (SCENT) Mapping CenterU54AG075936 · NIA · DUKE UNIVERSITY · PI LEE, PATTY J · 2021 to 2025
$12.7MNeuronal Autophagy: a Cell-Autonomous Protection MechanismR01NS060123 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zhenyu Yue · 2008 to 2026
$9.2MTNF ALPHA AND RECOVERY FROM ALCOHOLIC LIVER INJURYR01AA010154 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI ANNA MAE ELIZABETH DIEHL, Auinash Kalsotra · 1994 to 2026
$6.1MDetermining the neuroprotective mechanism for microglial autophagy in Alzheimer's diseaseR01AG072520 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI YUE, ZHENYU · 2021 to 2025
$4.2MAutophagy degradation of nuclear and chromatin constituentsR35GM137889 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI Zhixun Dou · 2020 to 2026
$2.6MSynthetic lethality by targeting the core senescent mechanism in lung cancer.R01CA244564 · NCI · DUKE UNIVERSITY · PI WANG, XIAO-FAN · 2020 to 2024
$2.4MDetermining Selective Autophagy Kinase in Modulating Neurotoxicity in Huntington's Disease ModelR01NS117590 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI YUE, ZHENYU · 2020 to 2024
$2.3MNucleus-to-cytoplasm trafficking of chromatin fragments in senescence and agingR01AG082785 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Zhixun Dou · 2023 to 2026
$2.2MSingle-cell proteomic identification of novel markers of senescenceUH3CA268117 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DOU, ZHIXUN, RAJAGOPAL, JAYARAJ · 2023 to 2024
$1.9MSingle-cell proteomic identification of novel markers of senescenceUG3CA268117 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DOU, ZHIXUN, RAJAGOPAL, JAYARAJ · 2021 to 2022
$1.2MNCATS NIH HHS UL1 TR002541NCI NIH HHS R01 CA244564NCI NIH HHS UG3 CA268117NCI NIH HHS UH3 CA268117NIAAA NIH HHS R01 AA010154NIA NIH HHS R00 AG053406NIA NIH HHS R01 AG072520NIA NIH HHS R01 AG082785NIA NIH HHS R21 AG073894NIA NIH HHS U54 AG075936NIDDK NIH HHS K01 DK135793NIDDK NIH HHS K08 DK139370NIDDK NIH HHS P30 DK040561NIGMS NIH HHS R35 GM137889NINDS NIH HHS R01 NS060123NINDS NIH HHS R01 NS117590
Abstract
Acute inflammation is an essential response that our bodies use to combat infections
Indexed as
AutophagyCell NucleusInflammationTranscription FactorsActive Transport, Cell NucleusAcute DiseaseAgingAnimalsAutophagosomesAutophagy-Related Protein 8 FamilyChromatinChromatin Assembly and DisassemblyChronic DiseaseDisease Models, AnimalFemaleHumansAutophagy-Related Protein 8 FamilyChromatinTranscription Factors
Identifiers
What Socratic holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.