Evidence map›Paper›PMID 40604458›Full record

Trial reportBMC geriatrics2025

Evaluating swallowing capacity in older adults with dysphagia: high protein, low carbohydrate smoothie formulas versus commercial formula.

Pichanun Mongkolsucharitkul, Bonggochpass Pinsawas, Thareerat Watcharachaisoponsiri, Sophida Suta, Sureeporn Pumeiam, Suphawan Ophakas, Apinya Surawit, Sunun Ongard, Phawin Keskool, Poungkaew Thitisakulchai and 2 more

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04901182 (The Effect of Nutrition-dense, Blenderized Enteral Nutrition From Natural Ingredients on Swallowing Capacity to Prevent Suffocation in the Elderly by Using Flexible Endoscopic Examination of Swallowing), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04901182 nacompletednot on this map

The Effect of Nutrition-dense, Blenderized Enteral Nutrition From Natural Ingredients on Swallowing Capacity to Prevent Suffocation in the Elderly by Using Flexible Endoscopic Examination of Swallowing (FEES)

TypeinterventionalSponsorMahidol UniversityRan2019 to 2019Enrolled63ConditionsDysphagiaArmsthe effect of consuming diets on the swallowing capacity by using Flexible Endoscopic Evaluation of Swallowing (FEES)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pichanun Mongkolsucharitkul *Siriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Bonggochpass Pinsawas *Siriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Thareerat WatcharachaisoponsiriSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Sophida SutaSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Sureeporn PumeiamSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Suphawan OphakasSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Apinya SurawitSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Sunun OngardDepartment of Otolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Phawin KeskoolDepartment of Otolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Poungkaew ThitisakulchaiDepartment of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Phisamai SrichayetInstitute of Food Research and Product Development, Kasetsart University, Bangkok, 10900, Thailand.
Korapat MayurasakornSiriraj Population Health and Nutrition Research Group (SPHERE), Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand. korapat.may@mahidol.ac.th.

Funding

Agricultural Research Development Agency PRP6105020390National Research Council of Thailand 105/2560
6 · The paper itself

Abstract

backgroundDysphagia is a common problem in older adults that can lead to nutritional deficiencies. Oral nutritional supplements (ONS) are products used for oral nutrition support as an alternative nutritional therapy, specifically manufactured for the older individuals at risk of dysphagia. This study aimed to develop four high protein (23-34% energy ratio) and low carbohydrate (25-38% energy ratio) smoothie formulas (white sesame (WS) vs. white sesame and low carbohydrate (WSLC) vs. black sesame and low carbohydrate (BSLC) vs. chicken shitake (CS); 1 kcal/ml) for the older people with dysphagia and to assess their effect on swallowing capacity compared to widely used commercial formula (Ensure

methodsA cross-sectional study involved 63 participants aged 65 years or over. Subjects were divided into asymptomatic (n = 32, aged 72.9 ± 5.66 year) or symptomatic swallowing difficulty (n = 31, aged 75.0 ± 6.48 year) groups based on swallowing screening questionnaires. Swallowing capacity was assessed using Fiberoptic Endoscopic Evaluation of Swallowing (FEES), performed by experienced physicians, for three drinks (WS, CS vs. Ensure

resultsSpare retention of a food bolus in each formula had been identified in the asymptomatic (47-66%) and symptomatic (61-71%) groups. WS had fewer premature spills than Ensure

conclusionsThe findings suggest that smoothie drinks, particularly WS (51-350 centipoise), may offer a viable alternative to commercial formula (1-50 centipoise) for older adults with dysphagia, potentially reducing premature spillage. The findings provide useful preliminary insights into the potential of these formulas to support safer swallowing. Further research, including longer-term studies, would help to more fully explore their nutritional benefits, safety, and applicability across broader populations.

trial registrationClinical Trial ID NCT04901182, https//clinicaltrials.gov/ct2/show/NCT04901182 (25/05/2021).

Indexed as

DeglutitionDeglutition DisordersDietary CarbohydratesDietary ProteinsFood, FormulatedAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleDietary CarbohydratesDietary ProteinsAgingDysphagiaSmoothie drinkSwallowing capacity

Identifiers

PMID40604458
PMCPMC12220473

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.