Evidence map›Paper›PMID 40604549›Full record

ArticleBMC nephrology2025

Effect of intradialytic dietary support on nutritional status, muscle strength, and clinical markers in patients on hemodialysis: a cross-sectional study.

Saadet Usakli, Safak Mirioglu, Mevlut Tamer Dincer, Beril Karatas, Cebrail Karaca

Abstract readMulticenter Study
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saadet UsakliDepartment of Internal Medicine, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey.ORCID 0009-0005-5368-9993
Safak MiriogluDivision of Nephrology, Department of Internal Medicine, Bezmialem Vakif University Hospital, Istanbul, Turkey.ORCID 0000-0003-0362-8154
Mevlut Tamer DincerDivision of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University - Cerrahpasa, Istanbul, Turkey.ORCID 0000-0002-5397-7697
Beril KaratasDivision of Nephrology, Department of Internal Medicine, Van Training and Research Hospital, Van, Turkey.ORCID 0000-0002-1660-8980
Cebrail KaracaDivision of Nephrology, Department of Internal Medicine, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey. cebrailkaraca@gmail.com.ORCID 0000-0003-0969-7708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntradialytic nutritional support influences nutritional status, muscle strength, and related clinical outcomes in patients undergoing hemodialysis (HD). This study aims to compare the effects of intradialytic nutrition on patient outcomes, malnutrition and sarcopenia risks, and handgrip strength (HGS) in HD patients.

methodsA cross-sectional study was conducted involving 129 HD patients (62 receiving intradialytic nutritional support and 67 not) from two HD centers located in the same geographic region. Nutritional status was assessed using the MNA-SF, while physical performance was evaluated with SARC-F and HGS. Biochemical markers, including serum albumin, phosphorus, potassium, and hemoglobin (Hb) levels, were measured.

resultsThe group receiving intradialytic nutritional support had significantly higher serum albumin (4.0 [3.7-4.2] g/dL vs. 3.5 [3.2-3.7] g/dL; p < 0.001, respectively) and potassium levels (5.6 [5.1-6.2] mmol/L vs. 5.0 [4.7-5.4] mmol/L; p < 0.001, respectively) compared to the group not receiving support. Phosphorus levels were similar between the two groups (4.8 [3.8-6.1] mg/dL vs. 5.3 [4.5-5.2] mg/dL; p = 0.059, respectively). The nutritional support group had lower Hb levels (10.9 ± 1.7 g/dL vs. 11.8 ± 2.0 g/dL; p = 0.008, respectively) and required higher doses of erythropoiesis-stimulating agents (32.0 [24.0-48.0] IU/month×10

conclusionIntradialytic nutritional support was associated with higher serum albumin levels and handgrip strength, with the latter being more prominent among male patients. However, potassium levels were found to be higher in the nutritional support group, which may present a clinical concern and warrants further monitoring. No significant differences were observed in malnutrition or sarcopenia risk. These findings highlight the potential benefits and limitations of intradialytic nutritional interventions and provide a basis for future prospective studies. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Kidney Failure, ChronicMuscle StrengthNutritional StatusNutritional SupportRenal DialysisAgedBiomarkersCross-Sectional StudiesFemaleHand StrengthHemoglobinsHumansMaleMalnutritionMiddle AgedPhosphorusBiomarkersHemoglobinsPhosphorusPotassiumSerum AlbuminHandgrip strengthHemodialysisIntradialytic nutritional supportMuscle strengthNutritional statusSarcopenia

Identifiers

PMID40604549
PMCPMC12220443

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.