Evidence map›Paper›PMID 40604612›Full record

ArticleBMC public health2025

Factors associated with parental literacy and hesitancy toward pediatric vaccination.

Yi Zheng, Paula M Frew, Dong Wang, Amanda L Eiden

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi ZhengBiostatistics and Research Decision Sciences, Merck & Co., Inc, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ, 07065, USA.
Paula M FrewGlobal Medical and Scientific Affairs, Merck & Co., Inc, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ, 07065, USA.
Dong WangBiostatistics and Research Decision Sciences, Merck & Co., Inc, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ, 07065, USA.
Amanda L EidenOutcomes Research, Merck & Co., Inc, 351 N Sumneytown Pike, North Wales, PA, 19454, USA. Amanda.Eiden@merck.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaccine literacy (knowledge about vaccines and the ability to identify accurate information about them) and vaccine hesitancy (delay in or refusal of vaccination) among parents may affect immunization decision-making and pediatric vaccine uptake. This study aimed to examine the demographic and socioeconomic characteristics of parents by vaccine literacy and hesitancy and to assess the relationship between attitudinal, behavioral, and experiential factors and parents' vaccine literacy and hesitancy.

methodsA cross-sectional survey was administered in 2022 to US adults aged ≥ 18 (N = 692) who self-identified as parents/guardians of children aged < 18. Parents were asked questions about their experiences assessing information on pediatric vaccinations, their information-seeking and decision-making practices, interactions with healthcare providers (HCPs) regarding pediatric vaccines, beliefs about vaccine efficacy and safety, trust in scientific and medical information from various sources, perceptions of the danger and severity of vaccine-preventable diseases, and the benefits and convenience of vaccination. High vaccine literacy was defined as being moderately or extremely familiar with the vaccines a child should receive. Vaccine hesitancy was defined as being somewhat or very hesitant, or not sure, about childhood immunizations (i.e., shots). An exploratory factor analysis reflected 7 discrete underlying variables describing self-reported behaviors, beliefs, and experiences regarding childhood vaccination.

resultsVaccine literacy and hesitancy were associated with parents' gender, race/ethnicity, education level, and urbanicity. Factors associated with increased vaccine literacy were positive interactions with HCPs (OR 2.24, P < 0.001), active information-seeking behavior (OR 1.88, P < 0.001), positive beliefs about vaccines (OR 1.39, P = 0.001), and beliefs about vaccination requirements (OR 1.21, P = 0.041). Trouble understanding information from HCPs was associated with decreased vaccine literacy (OR 0.80, P = 0.025). Factors associated with decreased vaccine hesitancy were positive beliefs about vaccines (OR 0.41, P < 0.001), minimal concerns over childhood vaccines (OR 0.46, P < 0.001), and positive interactions with HCPs (OR 0.76, P = 0.002). Increased hesitancy was associated with negative beliefs about vaccines (OR 3.26, P < 0.001) and trouble understanding information from HCPs (OR 1.44, P < 0.001).

conclusionsGreater vaccine literacy levels and less vaccine hesitancy correlated with positive parental beliefs about vaccines and positive interactions with HCPs. Challenges in comprehending HCP-delivered information were correlated with lower literacy and greater hesitancy.

Indexed as

Health Knowledge, Attitudes, PracticeHealth LiteracyParentsVaccinationVaccination HesitancyAdolescentAdultChildCross-Sectional StudiesFemaleHumansMaleMiddle AgedSocioeconomic FactorsSurveys and QuestionnairesUnited StatesCross-sectional studiesHealth literacyImmunizationVaccine confidenceVaccine hesitancyVaccine literacy

Identifiers

PMID40604612
PMCPMC12219603

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.