Evidence mapPaperPMID 40605156Full record

ReviewCurrent drug discovery technologies2026

Diverse Biological Activity of Pyrimidine Derivatives: A Review.

Anjali, Sumitra Nain

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug discovery technologies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

AnjaliDepartment of Pharmacy, Banasthali Vidyapith, Rajasthan, 304022, India.
Sumitra NainDepartment of Pharmacy, Banasthali Vidyapith, Rajasthan, 304022, India.ORCID 0000-0001-8238-3145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, a wide range of aromatic heterocyclic compounds are employed as therapeutics. Among these, pyrimidine is a well-known nucleus with two nitrogen atoms at the first and third positions of six-membered rings, with the chemical formula C4H4N2. In 1885, a physicist named Pinner coined the term "pyrimidine", which originates from "pyridine" and "amidine". Pyrimidine and its substituents have a variety of pharmacological and biological features. Research, drug discovery, and screening utilise the potential of this scafold. Significant therapeutic features such as antihypertensive, antimicrobial, anti-inflammatory, antimalarial, antihistaminic, sedatives and hypnotics, anticancer, and anti-human immunodeficiency virus (HIV) can be seen in the pyrimidine-containing compounds, as demonstrated by the literature. Search engines like Google, Google Scholar, ResearchGate, and ScienceDirect were used to obtain the information. In the future, in addition to helping with drug design and the development of pyrimidine derivatives as therapeutic drugs, this review paper offers insight into the different biological responses of compounds generated from pyrimidine.

Indexed as

PyrimidinesAnimalsAnti-Infective AgentsAntineoplastic AgentsDrug DesignDrug DiscoveryHumansAnti-Infective AgentsAntineoplastic AgentspyrimidinePyrimidinesantihypertensivebiological activityheterocyclic compoundsPyrimidinepyrimidine derivativestherapeutic drug

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.