Evidence map›Paper›PMID 40605464›Full record

ArticleAnnals of medicine2025

Evaluating muscle characteristics and fall events: insights from real-world longitudinal data.

Shaofang Li, Juchuan Dong, Caixia Zhao, Yongmei Li, Wenyuan Wang, Lijuan An, Yongqian Han, Fuhou Zhang, Lihua Jin

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaofang LiDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Juchuan DongDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID 0000-0003-1251-1118
Caixia ZhaoDepartment of Pediatrics, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Yongmei LiDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID 0009-0006-2785-6134
Wenyuan WangDepartment of Rehabilitation Medicine, Kunming Medical University, Kunming, Yunnan, China.ORCID 0009-0003-6004-0397
Lijuan AnDepartment of Rehabilitation Medicine, Kunming Medical University, Kunming, Yunnan, China.
Yongqian HanDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID 0000-0002-0187-5859
Fuhou ZhangDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Lihua JinDepartment of Rehabilitation Medicine, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID 0000-0002-5406-8815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the relationship between the delta values of muscle quantity (thickness) and muscle quality (grayscale) in the paretic and nonparetic lower extremities and the incidence of falls within 3 months. Muscle quality and quantity can significantly influence lower limb muscle strength in patients, potentially contributing to fall-related incidents.

settingRehabilitation department of the largest rehabilitation center in Southwest China's Yunnan Province.

participantsPatients with hemiplegic stroke or traumatic brain injury within the preceding 3 months. Exclusion criteria included the presence of other primary diseases that could contribute to muscle loss.

main outcome measuresBaseline characteristics, muscle thickness and grayscale measurements, inflammatory biomarkers, and total cholesterol levels were collected to evaluate patient-specific factors associated with subsequent falls after a 3-month period.

resultsCompared with patients with a manual muscle testing (MMT) score ≥3, those with an MMT score <3 exhibited significant differences in the rectus femoris (RF) (

conclusionReal-world, longitudinal data suggest that muscle grayscale, rather than muscle thickness, may offer superior prognostic insights. The likelihood of a falling event was elevated in patients with an MMT score <3, particularly among those with significant disparities in GM grayscale values between affected and unaffected limbs.

Indexed as

Accidental FallsBrain Injuries, TraumaticMuscle, SkeletalStrokeAdultAgedChinaFemaleHumansLongitudinal StudiesLower ExtremityMaleMiddle AgedMuscle StrengthFallingmusclereal-world datarectus femoris

Identifiers

PMID40605464
PMCPMC12231242

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.