Evidence map›Paper›PMID 40606040›Full record

ArticleAtherosclerosis plus2025

Proposed lipidology and preventive cardiology research priorities in Africa; Results of a Delphi survey.

Alexander R M Lyons, Frederick J Raal, Brett S Mansfield, David Marais, Neusa P J Jessen, Lambert T Appiah, Lilian Mbau, Bernard Samia, Ashraf Reda, Tigist S Mekonnen and 4 more

Abstract read
In one paragraph

Article in Atherosclerosis plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexander R M LyonsREOBSERV® Registry and Observational Scientific Solutions, UK.
Frederick J RaalCarbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Brett S MansfieldCarbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
David MaraisDivision of Chemical Pathology, Department of Pathology, Health Science Faculty, University of Cape Town, Cape Town, Western Cape Province, South Africa.
Neusa P J JessenFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Lambert T AppiahSchool of Medical sciences (KNUST-SMS), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Lilian MbauCentre for Cardiovascular Disease Prevention and Rehabilitation, Nairobi, Kenya.
Bernard SamiaMP Shah Hospital, Nairobi, Kenya.
Ashraf RedaCardiology department, College of Medicine, Menofia University, Shibin Al Kawm, Al Minufiyah, Egypt.
Tigist S MekonnenDepartment of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Albertino DamascenoFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Chala F OljiraDepartment of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Meral KayikciogluDepartment of Cardiology, Ege University Medical School, İzmir, Turkey.
Alberto ZambonDepartment of Medicine, University of Padua School of Medicine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite a population of over 1.5 billion, lipidology and preventive cardiology research of African origin is lacking in quantity and impact, and accounts for a small percentage of outputs globally due to limited resources to address the full breadth of unexplored research areas. We therefore conducted a Delphi survey on an expert panel of African clinical investigators to ascertain the proposed areas of priority to provide guidance on the future direction of African research in this field. Round one of the survey generated 58 proposed unanswered questions, and subsequent priority ratings of 1-5 of the proposed questions in two further rounds resulted in 42 priority research questions (PRQs) based on a two-thirds majority rating of 3-5 with 5 being the highest rating. Common themes amongst the 42 PRQs included mostly prevalence and distribution studies on hyperlipidaemia and lipid profiles and their risk of cardiovascular disease with emphasis on atherosclerotic cardiovascular disease, aortic stenosis, coronary artery disease, and acute coronary syndrome. The need for a cardiovascular risk score calculator appropriate for the different, diverse African populations was also emphasised. In conclusion, the results of this Delphi survey highlight a number of unanswered PRQs in lipidology and preventive cardiology in Africa that may be helpful to inform the strategic direction of future studies, education and funding in that underrepresented part of the world based on current priorities and may also have relevance globally.

Indexed as

AfricaDelphiDyslipidaemiaLipidologyPreventive cardiologyResearch prioritiesSurvey

Identifiers

PMID40606040
PMCPMC12213666

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.