Evidence map›Paper›PMID 40606290›Full record

ArticleCurrent developments in nutrition2025

The Role of Diet and Hormones on Taste: Low Carb Compared With Low Fat Study Findings.

Rosario B Jaime-Lara, Alexis T Franks, Nafisa Nawal, Meaghan C Steck, Ariana M Chao, Carolyn Allen, Brianna E Brooks, Monica Atkinson, Amber B Courville, Juen Guo and 7 more

Erratum issued Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current developments in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03878108 (Effect of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03878108 nacompletednot on this map

Effect of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism

TypeinterventionalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran2019 to 2020Enrolled21ConditionsHealthy, Healthy VolunteersArmsLCHF diet, LFHC diet
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Rosario B Jaime-LaraUniversity of California Los Angeles, UCLA School of Nursing, Los Angeles, CA, 20892, USA.
Alexis T FranksNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Nafisa NawalNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Meaghan C SteckNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Ariana M ChaoNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Carolyn AllenNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Brianna E BrooksNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Monica AtkinsonNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Amber B CourvilleNational Institute of Diabetes and Digestive and Kidney Diseases, Division of Intramural Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Juen GuoNational Institute of Diabetes and Digestive and Kidney Diseases, Division of Intramural Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Shanna YangClinical Center, Nutrition Department, National Institutes of Health, Bethesda, MD, 20892, USA.
Marinza MarzoukNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Valerie L DarceyNational Institute of Diabetes and Digestive and Kidney Diseases, Division of Intramural Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Stephanie ChungClinical Center, Nutrition Department, National Institutes of Health, Bethesda, MD, 20892, USA.
Ciarán G FordeWageningen University & Research, Division of Nutrition, Wageningen, Netherlands.
Kevin D HallNational Institute of Diabetes and Digestive and Kidney Diseases, Division of Intramural Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Paule V JosephNational Institute on Alcohol Abuse and Alcoholism, Division of Intramural Clinical and Biological Research, National Institutes of Health, Bethesda, MD, 20892, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As obesity rates escalate, weight-loss interventions, including low-carbohydrate (LC) and low-fat (LF) diets, have become popular. Although both diets promote weight loss, the effect of LC and LF diets on taste preference and sensitivity is less well understood. Objective: In this study, we sought to ( Methods: We analyzed and compared taste preference and detection after ad libitum, randomized, controlled inpatient feeding study ( Results: We found no significant differences in taste measures between the LC and LF diets. However, we did observe a negative association between salt preference and leptin levels during both LC (rs = 0.59; Conclusions: The results suggest that taste measures do not differ following 2-wk LC and LF diets. However, the relationship between taste preference and hunger and satiety hormones should be explored further.This trial was registered at www.clinicaltrial.gov as NCT03878108.

Indexed as

hunger and satiety hormonesketo dietlow-carbohydrate dietlow-fat diettaste detection thresholdtaste preference

Identifiers

PMID40606290
PMCPMC12219350

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.