Evidence map›Paper›PMID 40606466›Full record

ReviewFrontiers in medicine2025

Recent advances in crocodilian oil research: bioactive components and potential therapeutic applications.

Yuxi Huang, Xinyue Zheng, Xingchen Ming, Qiqi Jiao, Weihao Xiao, Qian Wu, Linyang Zheng, Yunfu Zeng, Shaowen Cheng, Rong Wang and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuxi Huang *The First Clinical College, Hainan Medical University, Haikou, China.
Xinyue Zheng *School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
Xingchen Ming *The Second Clinical College, Hainan Medical University, Haikou, China.
Qiqi JiaoThe First Clinical College, Hainan Medical University, Haikou, China.
Weihao XiaoEmblem of the Emergency and Trauma College, Hainan Medical University, Haikou, China.
Qian WuThe Second Clinical College, Hainan Medical University, Haikou, China.
Linyang ZhengKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Yunfu ZengKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Shaowen ChengKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Rong WangKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Jian YangKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Yangyang BianKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Jiangling YaoKey Laboratory of Emergency and Trauma of Ministry of Education, Wound Repair Department, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The economic value of crocodilian farming has risen substantially in recent years, drawing increasing attention to crocodilian oil as a traditional natural remedy rich in diverse bioactive constituents. Despite its therapeutic potential, crocodilian fat remains underutilized, and its nutritional and medicinal properties have not been widely recognized. This review provides a bibliometric analysis of past research trends and highlights current developments related to crocodilian oil. Recent advances in the characterization of its physicochemical properties and health-related applications are summarized. The primary biological activities of this oil are attributed to its high unsaturated fatty acid and stearic acid contents. Emerging evidence supports its anti-inflammatory, antimicrobial, and scar-reducing effects mediated through key signaling pathways, including p38 mitogen-activated protein kinase, transforming growth factor-β1/Smad3, and AMP-activated protein kinase. Reported benefits include improvements in skin conditions and the modulation of energy metabolism. Potential applications encompass adjunctive treatment for

Indexed as

anti-inflammatoryantimicrobial activitycrocodilian oilenergy metabolismscar reductionskin health

Identifiers

PMID40606466
PMCPMC12213835

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.