Evidence map›Paper›PMID 40606516›Full record

ReviewAmerican journal of preventive cardiology2025

Addressing adherence challenges in long-term statin treatment among Asian populations: Current gaps and proposed solutions.

Elmer Jasper B Llanes, Nuntakorn Thongtang, Zhen-Vin Lee, Tran Hoa, Ong Hean Yee, Renan Sukmawan

Abstract readReview
In one paragraph

Review in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Improving Lipid Profiles ThroughFoods (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elmer Jasper B LlanesDivision of Cardiovascular Medicine, University of the Philippines, Philippine General Hospital, Philippines.
Nuntakorn ThongtangDivision of Endocrinology and Metabolism, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand.
Zhen-Vin LeeDamansara Specialist Hospital 2, Malaysia.
Tran HoaHo Chi Minh City University Medical Centre, Vietnam.
Ong Hean YeeCardiac Solutions Medical Centre, Mount Elizabeth Hospital, Singapore.
Renan SukmawanNational Cardiovascular Center Harapan Kita, Cipto Mangunkusumo Hospital, Universitas Indonesia, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statin therapy, known for its lipid-lowering properties, substantially lowers the risk of cardiovascular events in patients vulnerable to atherosclerotic cardiovascular disease (ASCVD) across diverse demographic groups. Despite evidence supporting their benefits, statins are often underutilized or even discontinued. Disparities in statin utilization exist across Asian countries due to healthcare system policies and economic circumstances. Addressing these disparities is essential, especially in the context of global initiatives designed to enhance affordability and raise awareness. Healthcare practitioners (HCPs) must assess ASCVD risks and take proactive measures aimed at lowering these risks, particularly through the management of low-density lipoprotein cholesterol (LDL-C) levels. It is imperative for HCPs and patients to collaborate for effective management of ASCVD risk, prioritizing improved adherence, treatment continuity, and better health outcomes. This review focuses on statin utilization and adherence in six Asian countries-Thailand, Malaysia, Philippines, Vietnam, Singapore, and Indonesia. It aims to explore the common factors that influence long-term adherence to statin treatment and also offers practical recommendations to improve adherence, ultimately leading to better cardiovascular outcomes in the Asian population.

Indexed as

AdherenceAsian populationAtherosclerotic cardiovascular diseaseBarriersDyslipidemialong-term statin treatmentMedication adherence

Identifiers

PMID40606516
PMCPMC12213090

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.