Evidence map›Paper›PMID 40607221›Full record

ArticleFrontiers in endocrinology2025

Kentaro Sawano, Keisuke Nagasaki, Erina Suzuki, Yasuko Ogiwara, Ikuko Kageyama, Maki Fukami, Yoko Kuroki

Abstract readCase Reports
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kentaro SawanoDivision of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Keisuke NagasakiDivision of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Erina SuzukiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan.
Yasuko OgiwaraDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan.
Ikuko KageyamaDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan.
Maki FukamiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan.
Yoko KurokiDivision of Diversity Research, National Research Institute for Child Health and Development, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital hypogonadotropic hypogonadism (CHH) is a rare endocrine disorder characterized by gonadal dysfunction attributed to impaired gonadotropin secretion. CHH is associated with approximately 60 genes including

Indexed as

HypogonadismMutagenesis, InsertionalReceptor, Fibroblast Growth Factor, Type 1RetroelementsChildHigh-Throughput Nucleotide SequencingHumansMaleFGFR1 protein, humanReceptor, Fibroblast Growth Factor, Type 1RetroelementsAlu elementFGFR1hypogonadotropic hypogonadismlong-read NGSretrotransposon

Identifiers

PMID40607221
PMCPMC12213457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.