ArticleThe Pan African medical journal2025
Tuberculosis treatment adherence and associated factors in the Butha-Buthe district, Lesotho: a retrospective cohort study.
Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Factors associated with tuberculosis treatment adherence: reflections on a retrospective cohort study in Lesotho.The Pan African medical journal · 2026Article
- Determinants of Weight Gain Among Adult Tuberculosis Patients During Intensive Phase in East Gojjam Zone Public Health Institutions, Amhara Region, Ethiopia. A Cross-Sectional Study.Journal of nutrition and metabolism · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Lesotho remains one of the world's 30 high-tuberculosis (TB) burden countries. In Butha-Buthe district, unfavourable TB treatment outcomes were higher than those set forth by the WHO. This study's objective was to evaluate TB treatment adherence and treatment resistance among patients enrolled in the 12 health facilities in Butha-Buthe. Methods: data were collected from the medical records of patients with sputum smear-positive TB and extra-pulmonary forms of TB between January 2015 and December 2020. Results were presented in frequencies and percentages. Univariate and multivariable logistic regression analyses were conducted to identify factors associated with treatment adherence. Results: among 1,792 patients who were enrolled, 1,320 were included in the study. The overall mean TB treatment adherence rate was estimated at 37.20%. Factors found to be associated with treatment adherence in multivariate analysis were age ≥60 years (aOR: 0.59, 95%CI: 0.54- 0.66; P<0.001), being a mine worker (aOR 1.09, 95%CI: 1.03-1.14; P<0.001), having pulmonary TB (aOR: 1.23, 95%CI: 1.17-1.29, P<0.001), being in the continuation phase of the treatment (aOR 1.38, 95%CI: 1.33, 1.45; P<0.001) and category 2 (aOR 0.93, 95%CI: 0.88-0.99; P = 0.016). Regarding TB contact support, family members (aOR: 1.08, 95%CI: 1.03-1.14; P<0.001), friends (aOR 1.30, 95%CI: 1.19-1.41; P<0.001), spouses (aOR: 1.24, 95%CI 1.16-1.34; P<0.001), and unreported contacts (aOR 1.18, 95%CI: 1.09-1.27; P = 0.015) all showed increased TB adherence. Conclusion: the overall adherence to TB therapy was poor in Butha-Buthe district. Lesotho urgently needs district-level strategies to improve TB treatment adherence and reduce treatment resistance.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.