ArticleBrain and behavior2025
The Therapeutic Effects of Acorus Tatarinowii Volatile Oil and Electroacupuncture in Post-Stroke Cognitive Impairment Patients: A Clinical Trial Protocol.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Acorus tatarinowii volatile oil inhalation combined with Fengchi (GB20) acupuncture enhances cognitive recovery in post-stroke patients.American journal of translational research · 2026Article
- Plant Essential Oils and Chronic Inflammatory Diseases: A Panoramic View of Molecular Mechanisms.Drug design, development and therapy · 2026Review
- Efficacy of Huoxue Tongqiao Decoction combined with aniracetam in treating post-stroke cognitive impairment in elderly patients with ischemic stroke and its effects on serum levels of superoxide dismutase, glutathione peroxidase and nitric oxide.Pakistan journal of medical sciences · 2026Article
- Integrative neurobiological mechanisms of acupuncture in post-stroke cognitive impairment: from neurotransmission to brain network remodeling.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundPost-stroke cognitive impairment (PSCI) is a common complication following stroke, with limited effective treatments. This randomized controlled trial aims to evaluate the efficacy of two non-pharmacological interventions-electroacupuncture therapy (EA) and herbal olfactory therapy (HOT)-in improving cognitive function in PSCI patients, both as standalone treatments and in combination.
methodsThis parallel-group, assessor-blinded, randomized controlled trial will recruit 210 PSCI patients, randomly assigned to one of six groups: control, EA, HOT, combination therapy, sham therapy, or the healthy (ratio 1:1:1:1:1:1). All participants will receive standard cognitive training and basic medical care. The EA group will receive 4 weeks of electro-acupuncture at specific acupoints. The HOT group will receive 4 weeks of aromatic inhalation therapy using Acorus tatarinowii volatile oil. The combination group will receive both interventions. The primary outcome measure is cognitive function, assessed using the Montreal cognitive assessment (MoCA) at baseline, week 4, and week 8. Secondary outcomes include the mini-mental state examination (MMSE), functional magnetic resonance imaging (fMRI), near-infrared spectroscopy (fNIRS), and anxiety assessment using the state-trait anxiety inventory (STAI) at baseline and week 4. Data analysis will be conducted using a modified intention-to-treat approach.
aimsThis study aims to evaluate the clinical efficacy of EA at cervical acupoints combined with HOT for PSCI, with a specific focus on determining the therapeutic superiority of this combined approach over monotherapy interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.