Evidence map›Paper›PMID 40607757›Full record

ArticleACS applied materials & interfaces2025

Nanofibrillar Cellulose Hydrogels with Anionic Surface Modifications for Modulating Macrophage Phenotype in 3D Culture.

Maria Heilala, Rita Turpin, Nikolaos Pahimanolis, Nonappa, Olli Ikkala, Juha Klefström, Pauliina M Munne

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria HeilalaDepartment of Applied Physics, Aalto University. P.O. Box 15100, FI-00076 Aalto, Espoo Finland.ORCID 0000-0002-4237-4081
Rita TurpinCancer Cell Circuitry Laboratory, Translational Cancer Medicine, Medical Faculty, University of Helsinki. P.O. Box 63, Haartmaninkatu 8, FI-00014 Helsinki, Finland.
Nikolaos PahimanolisOy Keskuslaboratorio-Centrallaboratorium Ab, Tekniikantie 2, FI-02150 Espoo, Finland.
NonappaFaculty of Engineering and Natural Sciences, Tampere University. P.O. Box 541, FI-33720 Tampere, Finland.ORCID 0000-0002-6804-4128
Olli IkkalaDepartment of Applied Physics, Aalto University. P.O. Box 15100, FI-00076 Aalto, Espoo Finland.ORCID 0000-0002-0470-1889
Juha KlefströmCancer Cell Circuitry Laboratory, Translational Cancer Medicine, Medical Faculty, University of Helsinki. P.O. Box 63, Haartmaninkatu 8, FI-00014 Helsinki, Finland.
Pauliina M MunneCancer Cell Circuitry Laboratory, Translational Cancer Medicine, Medical Faculty, University of Helsinki. P.O. Box 63, Haartmaninkatu 8, FI-00014 Helsinki, Finland.ORCID 0000-0002-9720-9964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-inflammatory M2 macrophages are highly relevant in various physiological processes ranging from tissue regeneration to cancer progression. However, conventional two-dimensional (2D)

Indexed as

Cell Culture Techniques, Three DimensionalCelluloseHydrogelsMacrophagesNanofibersCell DifferentiationCytokinesHumansPhenotypeSurface PropertiesCelluloseCytokinesHydrogels3D cell culturehydrogelsmacrophage polarizationmacrophagesnanocelluloses

Identifiers

PMID40607757
PMCPMC12278226

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.