Evidence map›Paper›PMID 40608777›Full record

ArticlePloS one2025

Association of monocyte and lymphocyte ratio with risk of abdominal aortic calcification.

Wenting Yan, Tingting Hu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wenting YanDepartment of Cardiology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
Tingting HuDepartment of Cardiology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, China.ORCID https://orcid.org/0009-0004-0879-3882

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to evaluate the relationship between monocyte and lymphocyte ratio (MLR) with severe AAC.

methodsThis cross-sectional study enrolled 3041 patients with AAC from the National Health and Nutrition Examination Survey 2013-2014. Abdominal aortic calcification detected with dual-energy X-ray absorptiometry was quantified using the Kauppila score system. We measured white blood cell, neutrophil, lymphocyte counts, monocyte counts, red blood cell, calcium, 25-VitD3, and phosphorus levels in blood samples. Multivariate logistic regression was performed to examine the association between MLR (as a qualitative or quantitative variable) and severe AAC morbidity.

resultsSevere AAC was detected in 273 (9.0%) participants. Multivariate logistic regression analysis indicated that high MLR was an independent predictor of severe AAC (odds ratio [OR] 2.80, 95% confidence interval [CI] 1.04-7.50; P = 0.041).

conclusionsElevated MLR levels are independently associated with higher odds for severe AAC, which can serve as a new risk factor in clinical practice.

Indexed as

Aorta, AbdominalLymphocytesMonocytesVascular CalcificationAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysRisk Factors

Identifiers

PMID40608777
PMCPMC12225860

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.