Observational studyPediatric research2026
Cardiometabolic characteristics of school-aged children born preterm with very low birth weight.
Observational study in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Stop using "former": preterm birth and cardiometabolic risk to future health.Pediatric research · 2026Review
- Cardio-Metabolic Risk in Adults Born Preterm: A Narrative Review.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm birth is a risk factor for early-onset cardiovascular and metabolic diseases. However, there is a paucity of data related to cardiometabolic health of preterm individuals from low- and middle-income countries. Our aim was to investigate the cardiometabolic characteristics of school-age children born preterm with very low birth weight (VLBW) compared to term.
methodsThis cross-sectional observational study recruited 77 children born preterm VLBW in Southern Brazil and 59 term children, aged 8-14 years old. Physical exam, body composition and fasting blood tests were performed. Cardiometabolic risk factors were determined as elevated blood pressure (BP), overweight, dyslipidemia, and dysglycemia.
resultsPreterm group presented an OR of 2.6 (95% CI 1.05, 6.6) for elevated BP compared to term. Overweight was less common in the preterm (OR 0.4; 95% CI 0.2, 0.9). Dyslipidemia and dysglycemia were not different among groups, with both conditions highly prevalent across them. Preterm group presented lower fat mass (-4.6 kg; 95% CI -7.4, -1.8) and fat-free mass (-2.33 kg; 95% CI -4.27, -0.40) compared to term; lower-income preterm children exhibited higher fat mass. Eutrophic preterm subgroup analysis evidenced elevated triglycerides.
conclusionChildren born preterm with VLBW in a LMIC present increased risk for cardiovascular diseases. Eutrophic and lower-income preterm children presented higher cardiometabolic risk, justifying long-term monitoring for adverse outcomes. IMPACT: School-aged children born preterm with very low birth weight, particularly from low-income families, showed increased risk of cardiac and metabolic diseases. This pioneering study of juvenile individuals born preterm in Brazil offers valuable insights into the long-term effects of preterm birth, a field largely explored in the literature from high-income countries. The prevalence of cardiometabolic risk factors-elevated blood pressure, dysglycemia, dyslipidemia, and overweight, in preterm born children is a subject of great concern. Our findings highlight the need for extended follow-up to improve outcomes in high-risk preterm individuals.
Indexed as
Identifiers
40610709What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.