Evidence map›Paper›PMID 40611005›Full record

ReviewBMC surgery2025

Challenges and strategies for optimizing liver transplantation outcomes in morbidly obese cirrhotic patients: a narrative review.

Srinivasan Muthukrishnan, Jason Zhou, Richard Wang, Jerry Bohlen, Raphael Meier, Kirti Shetty, Chandra Bhati

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Srinivasan Muthukrishnan *Division of Transplantation, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Jason Zhou *University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Richard WangUniversity of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Jerry BohlenUniversity of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Raphael MeierDivision of Transplantation, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Kirti ShettyDivision of Gastroenterology and Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Chandra BhatiDivision of Transplantation, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. CBhati@som.umaryland.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising prevalence of morbid obesity (BMI > = 40) has introduced significant challenges in liver transplantation, particularly as metabolic dysfunction-associated steatohepatitis (MASH) becomes a leading cause of end-stage liver disease. Morbidly obese transplant candidates face higher perioperative complications, increased waitlist mortality, and worse post-transplant outcomes. This review explores these challenges and examines current strategies for managing morbid obesity in this population. Pre-operative weight loss and bariatric surgery prior to or in conjunction with transplantation have shown potential to improve eligibility and outcomes. Furthermore, emerging evidence suggests that BMI matching seems to influence graft function and survival. Finally, surgical techniques, such as robotic-assisted liver transplantation, while still novel and anecdotal, offer significant promise for reducing complications in this high-risk population.

Indexed as

End Stage Liver DiseaseLiver CirrhosisLiver TransplantationObesity, MorbidBariatric SurgeryHumansPostoperative ComplicationsTreatment OutcomeBariatric surgeryLiver transplantMorbidly obesePerioperative risksPreoperative weight lossrobotic-assisted liver transplantationWaitlist mortality

Identifiers

PMID40611005
PMCPMC12232003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.