Evidence mapPaperPMID 40611468Full record

ReviewNeurodegenerative disease management2025

Fruits as a preventative strategy: exploring their role in neurodegenerative disease management.

Bhavani Sowndharya B, Rupesh K Gautam, Mathan Muthu C M, Bharath S, Vickram A S, Saravanan A, Gulothungan G, Hitesh Chopra

Abstract readReview
In one paragraph

Review in Neurodegenerative disease management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bhavani Sowndharya BDepartment of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, India.
Rupesh K GautamDepartment of Pharmacology, Indore Institute of Pharmacy, Indore, India.
Mathan Muthu C MDepartment of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, India.
Bharath SDepartment of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, India.
Vickram A SDepartment of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, India.
Saravanan ADepartment of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, India.
Gulothungan GDepartment of Electronics and Communication Engineering, SRM Institute of Science and Technology, Chengalpattu, India.
Hitesh ChopraCentre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fruits' popularity has grown due to their ability to protect against neurodegenerative illnesses and to be an important dietary component for good brain activity. This review focuses on fruits' potential for preventing such, taking into account their bioactive compounds and mode of action. It emphasizes the abundance of flavonoids, polyphenols, vitamins, and minerals found in berries, citrus, and other tropical fruits, which have been shown to reduce oxidative damage, prevent neuroinflammation, and improve synaptic plasticity. There is an extensive literature on the neuroprotective actions of compounds such as resveratrol, quercetin, and anthocyanins in neurogenesis and mitochondrial process functions. The review also mentions emerging literature with the gut-brain axis, where it underscores the way in which fruit-derived prebiotics and dietary fibers regulate gut microbiota, which in turn affects brain health. This study analyzes gaps by adopting a comprehensive approach to studying fruits' preventive power in the treatment of neurodegenerative illness. This study combines molecular biology, clinical trial, and dietary science findings to highlight the use of fruits in ordinary diets as a sustainable, natural way of promoting neuroprotection and slowing the course of NDs.

Indexed as

FruitNeurodegenerative DiseasesNeuroprotective AgentsGastrointestinal MicrobiomeHumansNeuroprotective Agentsdietary antioxidant sourcesfruit-derived bioactive compoundsfruits and neuroprotectionNeurodegenerative diseasesneuroinflammation modulation

Identifiers

PMID40611468
PMCPMC12952739

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.