ArticleFrontiers in nutrition2025
Abdominal obesity and osteoarthritis risk: evaluating the association of lipid accumulation product, body roundness index, and waist triglyceride index with osteoarthritis in U.S. adults.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Is multi-joint hip and knee osteoarthritis more than the sum of its parts?Osteoarthritis and cartilage open · 2026Article
- Association of Triglyceride-to-HDL Cholesterol Ratio with Osteoarthritis: Multicenter Evidence and Application of an Interactive Risk Visualization Tool.Journal of inflammation research · 2026Article
- Association between obesity indices, insulin resistance markers, and osteoarthritis in middle-aged and elderly Chinese adults.Frontiers in nutrition · 2025Article
- Impact of the lipid-inflammation axis on endometriosis risk: a multicenter case-control study using mediation analysis.Frontiers in endocrinology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study explored the associations between lipid accumulation product (LAP), body roundness index (BRI), and waist triglyceride index (WTI) and osteoarthritis (OA) in U.S. adults, using data from National Health and Nutrition Examination Survey (NHANES) 2015-2018. Methods: This cross-sectional analysis included 3,611 participants aged ≥20 years. Using survey-weighted procedures, multivariable logistic regression assessed associations between anthropometric indices and OA. Smooth curve fitting evaluated non-linear relationships and threshold effects. Segmented linear regression was applied to identify potential inflection points. Subgroup analyses explored demographic and health-related variations, while receiver operating characteristic (ROC) curves assessed the discriminative capacity of these anthropometric indices. Results: Among participants, 517 (14.31%) had OA. All indices showed positive associations with OA after adjustment: LAP (OR: 1.19, CI: 1.13-1.25), BRI (OR: 1.02, CI: 1.01-1.02), and WTI (OR: 3.72, CI: 2.25-6.16). LAP significantly increased OA risk below 131.16 (OR: 1.02, Conclusion: Central obesity-related indices demonstrate significant associations with OA prevalence in U.S. adults, with distinct threshold effects for LAP and WTI. These indices, particularly BRI, may serve as valuable screening tools for OA risk assessment in clinical practice.
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