Evidence map›Paper›PMID 40612565›Full record

ArticleClinical kidney journal2025

Chronic kidney disease is associated with incident depression requiring treatment: a retrospective cohort study.

Andreas Kommer, Paul Christoph Claßen, Eva Maria Schleicher, Julia Weinmann-Menke, Karel Kostev, Christian Labenz

Abstract read
In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreas KommerDepartment of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Paul Christoph ClaßenDepartment of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Eva Maria SchleicherDepartment of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Julia Weinmann-MenkeDepartment of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.ORCID https://orcid.org/0000-0001-7344-8381
Karel KostevEpidemiology, IQVIA, Frankfurt, Germany.ORCID https://orcid.org/0000-0002-2124-7227
Christian LabenzDepartment of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.ORCID https://orcid.org/0000-0001-8390-9663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression is one of the most common psychiatric condition in patients with chronic kidney disease (CKD). It is associated with decreased adherence and quality of life as well as increased risk for dialysis, hospitalization, and mortality. Large population-based analysis evaluating the effect of CKD on the incidence of depression are missing. Methods: We performed a retrospective cohort study investigating the incidence of depression after CKD diagnosis in a large cohort derived from the IQVIA Results: Both cohorts included 165 787 individuals each, either with or without CKD. The 10-year incidence of depression was 24.2% in patients with CKD and 22.2% in patients without CKD ( Conclusion: In this large cohort, CKD is associated with a slightly higher incidence of depression requiring drug treatment. Clinicians caring for patients with CKD, especially younger patients, should be aware of the increased risk.

Indexed as

antipsychoticsdepressionkidney diseasemood disorders

Identifiers

PMID40612565
PMCPMC12223368

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.