Evidence map›Paper›PMID 40613787›Full record

Trial reportThe British journal of surgery2025

Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial.

Ilmari Saarinen, Marjatta Strandberg, Saija Hurme, Mika Helmiö, Sofia Grönroos, Anne Juuti, Risto Juusela, Pirjo Nuutila, Paulina Salminen

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter StudyComparative Study
In one paragraph

Trial report in The British journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00793143 (A Randomized Prospective Three-center Study), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00793143 completednot on this map

A Randomized Prospective Three-center Study: Laparoscopic Gastric Bypass vs. Laparoscopic Sleeve Gastrectomy in the Treatment of Morbid Obesity

TypeobservationalSponsorTurku University HospitalRan2008 to 2010Enrolled240ConditionsMorbid Obesity
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ilmari SaarinenDepartment of Digestive Surgery, Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
Marjatta StrandbergEmergency Care, Turku University Hospital, Turku, Finland.
Saija HurmeDepartment of Biostatistics, University of Turku and Turku University Hospital, Turku, Finland.
Mika HelmiöDepartment of Digestive Surgery, Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
Sofia GrönroosDepartment of Digestive Surgery, Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
Anne JuutiDepartment of Abdominal Surgery, Abdominal Centre, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Risto JuuselaDepartment of Surgery, Vaasa Central Hospital, Vaasa, Finland.
Pirjo NuutilaDepartment of Endocrinology, Turku University Hospital, Turku, Finland.
Paulina SalminenDepartment of Digestive Surgery, Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.ORCID 0000-0001-6435-9264

Funding

EVO FoundationFinnish Cultural FoundationMary and Georg C. Ehrnrooth FoundationPaulo FoundationSatakunta Regional FundTurku University Hospital
6 · The paper itself

Abstract

backgroundLong-term data on the prevalence of nutritional deficiencies after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) in RCTs are lacking. The aim of this study was to compare nutritional deficiencies and adherence to vitamin supplements after LSG and LRYGB at 10 years.

methodsThis was a predefined secondary analysis of the Finnish SLEEVEPASS (LSG versus LRYGB for severe obesity) multicentre RCT, with 10-year nutritional laboratory measurements and completed questionnaires on micronutrient supplement use, to assess the prevalence of micronutritional and macronutritional deficiencies and adherence.

resultsOf 240 patients (121 LSG patients and 119 LRYGB patients), 228 were available for 10-year follow-up. Of these 228 patients, 190 (83.3%) were available for laboratory tests and 192 (84.2%) for questionnaires. There were no statistically significant differences between LSG and LRYGB in the prevalence of vitamin D insufficiency (10 of 94 (11%) versus 9 of 84 (11%) respectively; P = 0.545), the prevalence of hypocalcaemia (3 of 92 (3%) versus 1 of 83 (1%) respectively; P = 0.088), the prevalence of vitamin B12 deficiency (2 of 46 (5%) versus 0 of 45 (0%); P = 0.240), or mean vitamin B12 levels (P = 0.939). The prevalence of iron deficiency, defined by ferritin level, was statistically significantly lower after LSG compared with LRYGB (4 of 29 (14%) versus 12 of 29 (41%); P = 0.017), with a median ferritin level of 34 (interquartile range 20-54) µg/l after LSG and 20 (interquartile range 12-117) µg/l after LRYGB (P = 0.397). The LSG group had statistically significantly lower overall adherence to micronutritional supplements (70 of 99 (71%) versus 83 of 93 (89%) respectively; P = 0.002).

conclusionLong-term micronutritional and macronutritional deficiencies were rare after both LSG and LRYGB, with similar deficiency rates. Only the prevalence of iron deficiency was more common after LRYGB compared with LSG. The overall adherence to micronutritional supplements was lower after LSG. REGISTRATION NUMBER: NCT00793143 (http://www.clinicaltrials.gov).

Indexed as

GastrectomyGastric BypassMalnutritionObesity, MorbidAdultDietary SupplementsFemaleFinlandFollow-Up StudiesHumansLaparoscopyMaleMicronutrientsMiddle AgedPostoperative ComplicationsPrevalenceMicronutrients

Identifiers

PMID40613787
PMCPMC12231607

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.