Evidence map›Paper›PMID 40615328›Full record

SynthesisBritish journal of anaesthesia2025

Adherence to prehabilitation in adult surgical patients: a systematic review, meta-analysis, meta-regression, and qualitative synthesis.

Marta I Berrio-Valencia, Mariam Al-Bayati, Adir Baxi, Karina Branje, Ingrid Chitiva-Martinez, Emily Hladkowicz, Gurlavine Kidd, Brian Hutton, Dianna M Wolfe, Manoj Lalu and 4 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Rethinking Perioperative Care in Older Adults: A Plea for Specialization.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marta I Berrio-ValenciaDepartment of Anaesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada.
Mariam Al-BayatiMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Adir BaxiMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Karina BranjeMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Ingrid Chitiva-MartinezDepartment of Anaesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada.
Emily HladkowiczMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Gurlavine KiddPatient Partner, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Brian HuttonMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Dianna M WolfeMethodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Manoj LaluDepartment of Anaesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; Methodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Sylvain BoetDepartment of Anaesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada.
Chelsia GillisDepartment of Anaesthesia, McGill University, Montreal, QC, Canada.
Daniel I McIsaacDepartment of Anaesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; Methodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, ON, Canada; School of Epidemiology & Public Health, University of Ottawa, Ottawa, ON, Canada. Electronic address: dmcisaac@toh.ca.
Canadian Prehabilitation Knowledge Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrehabilitation is hypothesised to play an important role in optimising postoperative outcomes. However, achieving high adherence can be challenging. Our objectives were to synthesise current approaches to adherence measurement and reporting, estimate prehabilitation adherence across trials, identify procedural-, programme-, or patient-level factors associated with adherence, and report barriers and facilitators to adherence.

methodsOvid MEDLINE, Embase, the CINAHL, PsycINFO, Web of Science, and the Cochrane CENTRAL Register of Controlled Trials were searched from inception until April 10, 2024. We included randomised trials of adults undergoing major elective surgery allocated to a prehabilitation programme, with at least one binary or continuous measure of adherence to prehabilitation, to an individual component, or both. Random-effects meta-analysis pooled overall adherence rates; meta-regression evaluated predictors of adherence. Qualitative synthesis of reported barriers and facilitators was informed by the Theoretical Domains Framework.

resultsWe screened 11 652 titles and abstracts, followed by 1232 full texts, and included 105 trials (n=4941). Pooled adherence was 79% (95% confidence interval [CI] 70-88; I

conclusionsPrehabilitation adherence metrics are variable across trials and standardisation is required to improve reporting and interpretation of prehabilitation evidence. Little credible evidence identifies factors associated with adherence; however, qualitative barriers and facilitators could inform programme design and implementation. SYSTEMATIC REVIEW PROTOCOL: PROSPERO (CRD42024518851).

Indexed as

Elective Surgical ProceduresPatient CompliancePreoperative CarePreoperative ExerciseAdultHumansRandomized Controlled Trials as Topicadherenceexercisenutritionprediction modelsprehabilitationqualitative methodssystematic review

Identifiers

PMID40615328
PMCPMC12489362

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.