ArticleBMC urology2025
Lower urinary tract symptoms (LUTS) and sleep quality: the mediating role of anxiety and depression in middle-aged and older adults from the ardakan cohort study on aging (ACSA).
Article in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Lower Urinary Tract Symptoms and Cognitive Impairment Among Participants in the REGARDS Cohort Study.Journal of the American Geriatrics Society · 2026Article
- Community Prevalence and Predictors of Pelvic Floor-Related Symptoms in Saudi Men: Implications for Physiotherapy-Led Care.Healthcare (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study investigated the prevalence of LUTS and its relationship with sleep quality in Iranian older adult.
methodsThe data used in this cross-sectional study were extracted from the first phase of the Ardakan Cohort Study on Aging (ACSA). The study included 2716 men aged ≥ 50 years living in Ardakan City. The Pittsburg Sleep Quality Index (PSQI) and International Prostatism Symptom Score (IPSS) questionnaires were used to measure sleep quality and LUTS, respectively. Confirmatory Factor Analysis (CFA) was used to examine the relationship between LUTS and sleep quality, considering the mediating role of anxiety and depression.
resultsThe average age of the men was 63.3 ± 8.2 years. The prevalence of moderate LUTS was 20.9% (CI: 19.4 - 22.4%), and severe LUTS was 4.4% (CI: 3.7 - 5.3%). A statistically significant positive correlation was observed between sleep quality with LUTS (r = 0.21, P-value < 0.001), depression (r = 0.45, P-value < 0.001), and anxiety (r = 0.40, P-value < 0.001). LUTS leads to poor sleep quality directly (β = 0.08, P-value = 0.03) and indirectly, considering the mediating role of depression and anxiety factors (β = 0.25, P-value = 0.007).
conclusionThe prevalence of LUTS among middle-aged and older adults in Ardakan city was lower compared to similar populations elsewhere. Additionally, LUTS affects sleep quality in individuals over 50 both directly and indirectly through anxiety and depression.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.