Evidence map›Paper›PMID 40615959›Full record

Observational studyBMC primary care2025

Time is health: management of Parkinson's disease in primary care: a retrospective quantitative study of diagnostic and therapeutic timelines.

Sabine Bayen, Xavier Lagon, Charles Cauet, Marc Bayen, Teddy Richebe, Nassir Messaadi, Matthieu Calafiore

Abstract readObservational Study
In one paragraph

Observational study in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabine BayenDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France. sabine.bayen@univ-lille.fr.ORCID 0000-0002-3334-9394
Xavier LagonDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0009-0006-3030-0647
Charles CauetDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0009-0008-4988-6187
Marc BayenDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0000-0002-9355-3434
Teddy RichebeDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0009-0006-6636-8467
Nassir MessaadiDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0000-0002-3602-7120
Matthieu CalafioreDistrict of General Practice, UFR3S, Pôle formation Faculté de médecine H. Warembourg 59045 Lille CEDEX 1, UFR3S, University of Lille, 1, Place de Verdun, Lille, 59045, France.ORCID 0000-0002-4755-5172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson’s disease is a neurodegenerative disorder which can be difficult to diagnose due to the non-specificity of the initial symptoms. The objective of our study was to objectify and quantify the delay of the diagnostic process and to identify the factors that influence it.

methodsAn exploratory quantitative, cross-sectional, retrospective, observational study was conducted from 22 March 2023 to 31 March 2024 among general practitioners (GPs) practising in France who were asked to study their patient files concerning the care pathways of their patients with Parkinson’s disease. The data was collected using a standardised, anonymised online questionnaire (Limesurvey®), the link to which was distributed via email. The questionnaire provided detailed information on the key dates of diagnosis and follow-up, and on the symptoms reported by patients and documented by doctors.

resultsThe diagnostic pathway for Parkinson’s disease is substantiated by the observation of protracted delays. On average, patients take more than three years to obtain a formal diagnosis and to receive appropriate treatment. The delays experienced are primarily attributable to prodromal non-visible non-motor symptoms, for which referral delays are tripled in comparison to visible motor symptoms. Challenges in accessing a neurologist and the frequent necessity for unnecessary complementary exams also contribute to the delays.

conclusionOur results underscore the pivotal role of GPs in the early detection of Parkinson’s disease, particularly in its prodromal stage marked by non-visible non-motor symptoms. While the diagnostic hypothesis was confirmed in most cases (70%) by neurologists, specific training of GPs in Parkinson’s disease with recognition of non-motor symptoms and treatment initiation would accelerate the process of diagnosis and referral to a neurologist and potentially reduce diagnostic and therapeutic times.

Indexed as

Delayed DiagnosisParkinson DiseasePrimary Health CareAgedCross-Sectional StudiesFemaleFranceHumansMaleMiddle AgedProdromal SymptomsReferral and ConsultationRetrospective StudiesSurveys and QuestionnairesTime FactorsTreatment DelayDelayed diagnosisDiagnosisParkinson's diseasePrimary careTimelines

Identifiers

PMID40615959
PMCPMC12226921

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.