ArticleBMC neurology2025
Stroke burden in North Africa and the Middle East, 1990-2021: an analysis based on the global burden of disease study.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management.MedComm · 2026Review
- Prevalence of stroke in young adults in the Middle East and North Africa Region: A systematic review and meta-analysis.PLOS global public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveThis study provides updated estimates of stroke burden, risk factors, and their trends in North Africa and Middle East (NAME) region from 1990 to 2021, which are essential for effective healthcare and resource allocation.
methodsData were obtained from the Global Burden of Disease (GBD) 2021 study, which provides comprehensive epidemiological estimates for stroke across 21 countries in the NAME super region. We calculated age-standardized rates for prevalence, incidence, mortality, and disability-adjusted life years (DALYs) using the GBD standard population. Decomposition analysis was conducted to assess the contributions of population growth, aging, and changes in age-specific incidence rates to the overall stroke burden.
resultsThere was a significant increase in absolute numbers of stroke cases, deaths, and DALYs in the NAME region from 1990 to 2021, with a total of 614,803.8 new stroke cases in 2021, representing a 101.2% increase since 1990. Despite this rise, age-standardized rates for incidence, mortality, and DALYs decreased significantly. High systolic blood pressure, air pollution, and high level of low-density lipoprotein cholesterol (LDL-C) were identified as the leading risk factors contributing to stroke mortality in the region in 2021.
conclusionStroke remains a pressing public health issue in the NAME region, marked by rising absolute case numbers but declining age-standardized rates. This trend may reflect improvements in stroke awareness, early detection, and medical advancements, though the extent varies across countries. Significant disparities exist, as lower-income nations face greater challenges in prevention, acute care, and rehabilitation compared to higher-income countries with better healthcare infrastructure. Addressing these gaps through targeted policies and resource allocation is crucial to improving stroke outcomes across the region.
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Registered trials
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