ArticlePorcine health management2025
Dietary supplementation of Galactooligosaccharides improves growth performance and intestinal barrier function of offspring.
Article in Porcine health management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Galacto-Oligosaccharides Reshape MucinJournal of agricultural and food chemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This study aims to investigate the effects of maternal supplementation with galactooligosaccharides (GOS) on intestinal digestion, absorption, and barrier function of offspring. Twenty four late-pregnant Ningxiang sows were randomly assigned into 3 treatments, including basic diet, basic diet with 0.5% GOS, basic diet with 100 mg/kg aureomycin, 20mg/kg ciprofloxacin and 10mg/kg vancomycin. The results showed that maternal dietary supplementation of GOS increased the body weight and average daily gain, reduced the diarrhea score of piglets, and increased the activities of digestive enzymes including maltase and α-amylase. Maternal GOS improved the intestinal barrier integrity and function of piglets, which exhibiting with increased ileal ratio of villus to crypt, and higher expressions of secretory immunoglobulin A, tight junction protein and mucin-2 in ileum. Maternal GOS treatment increased the contents of anti-inflammatory factors IL-4, IL-10 and TGF-β, but decreased the contents of pro-inflammatory factors IL-1β, IL-6 in the ileum and colon of piglets. In addition, piglets in maternal GOS treatment had increased abundance of probiotics in the colonic contents, as well as higher short-chain fatty acids concentrations in the colonic and cecal contents. Overall, this study provides data support for the nutritional regulation of maternal supplementation with 0.5% GOS to promote intestinal health of offspring.
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Registered trials
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