Evidence map›Paper›PMID 40619366›Full record

ArticleBMC medicine2025

Predictors and outcomes associated with prolonged hospital length of stay in intracerebral hemorrhage: a multicenter prospective cohort study in China.

Zhuangzhuang Zhang, Jieyu Li, Wenzhe Wang, Haowei Wang, Junlong Shu, Haiqiang Jin, Peng Sun, Craig S Anderson, Zhaoxia Wang, Yining Huang and 2 more

Abstract readMulticenter Study
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhuangzhuang ZhangDepartment of Neurology, Peking University First Hospital, Beijing, China.
Jieyu LiDepartment of Neurology, Peking University First Hospital, Beijing, China.
Wenzhe WangDepartment of Neurology, Peking University First Hospital, Beijing, China.
Haowei WangDepartment of Neurology, Peking University First Hospital, Beijing, China.
Junlong ShuDepartment of Neurology, Peking University First Hospital, Beijing, China.
Haiqiang JinDepartment of Neurology, Peking University First Hospital, Beijing, China.
Peng SunDepartment of Neurology, Peking University First Hospital, Beijing, China.
Craig S AndersonThe George Institute for Global Health, Royal Prince Alfred Hospital and the University of New South Wales, Sydney, Australia.
Zhaoxia WangDepartment of Neurology, Peking University First Hospital, Beijing, China.
Yining HuangDepartment of Neurology, Peking University First Hospital, Beijing, China.
Weiping SunDepartment of Neurology, Peking University First Hospital, Beijing, China. sunweiping@bjmu.edu.cn.
ChinaQUEST (Quality Evaluation of Stroke Care and Treatment) Investigators

Funding

National High Level Hospital Clinical Research Funding (Interdepartmental Research Project of Peking University First Hospital) 2023IR29National Natural Science Foundation of China Grant No. 81400944the Interdisciplinary Clinical Research Project of Peking University First Hospital No. 2021CR37
6 · The paper itself

Abstract

backgroundResearch on factors influencing prolonged length of stay (LOS) and its impact on prognosis in intracerebral hemorrhage (ICH) patients is limited. This study aimed to identify clinical predictors associated with prolonged LOS and to explore the potential impact of prolonged LOS on the prognosis of patients with mild to moderate ICH.

methodsThe study included mild to moderate ICH patients from the China Quality Evaluation of Stroke Care and Treatment (QUEST) database. Prolonged LOS was defined as a hospitalization exceeding 14 days. Sociodemographic characteristics, medical histories, stroke severity, in-hospital treatments, complications, discharge destination, and hospital characteristics were compared between the prolonged and normal LOS groups to screen for the potential predictors of extending LOS after ICH. The outcomes were the proportions of poor outcome at 3 months and 12 months after stroke onset. Poor outcome was defined as an mRS score of 3-5 or death.

resultsA total of 1055 mild to moderate ICH patients were enrolled in the study, with 281 (26.6%) exhibiting a LOS of 14 days or less, and 774 (73.4%) exceeding 14 days. The multivariable logistic regression analysis identified several independent predictors of prolonged LOS including younger age, higher annual household income, possession of medical insurance, a history of antithrombotic medication use, infection complication during hospitalization, and hospital regions. Unadjusted analyses showed there were no significant differences in the risk of poor outcome between the prolonged and normal LOS groups at 3 and 12 months after ICH (OR 0.89, 95% CI 0.67-1.17, P = 0.404; OR 0.82, 95% CI 0.61-1.09, P = 0.165). The adjusted models and the sensitivity analysis using propensity score matching and subgroup analysis produced the similar results.

conclusionsVarious factors contributed to prolonged LOS in mild to moderate ICH patients, including younger age, higher annual household income, possession of medical insurance, a history of antithrombotic medication use, the occurrence of infections during hospitalization, and the hospital regions. A prolonged LOS exceeding 14 days was not associated with a better functional outcome for mild to moderate ICH patients at 3 and 12 months.

Indexed as

Cerebral HemorrhageLength of StayAgedAged, 80 and overChinaFemaleHumansMaleMiddle AgedPrognosisProspective StudiesRisk FactorsIntracerebral hemorrhageLength of stayOutcomePredictors

Identifiers

PMID40619366
PMCPMC12232577

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.