Evidence map›Paper›PMID 40619690›Full record

ArticleSynapse (New York, N.Y.)2025

[

Fariha Karim, Brooke A Delaney, Rommani Mondal, Christopher Liang, Geidy E Serrano, Thomas G Beach, Jogeshwar Mukherjee

Abstract read
In one paragraph

Article in Synapse (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Evaluation of [Acta neuropathologica communications · 2026
    Article
  2. Article
  3. Article
  4. Evaluation of [Research square · 2026
    Article
  5. Synthesis and Evaluation of Radioiodinated [Journal of labelled compounds & radiopharmaceuticals · 2026
    Article
  6. Assessment of [Biomolecules · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fariha KarimDepartment of Radiological Sciences, Preclinical Imaging, University of California-Irvine, Irvine, California, USA.ORCID 0009-0001-3104-9523
Brooke A DelaneyDepartment of Radiological Sciences, Preclinical Imaging, University of California-Irvine, Irvine, California, USA.
Rommani MondalDepartment of Radiological Sciences, Preclinical Imaging, University of California-Irvine, Irvine, California, USA.
Christopher LiangDepartment of Radiological Sciences, Preclinical Imaging, University of California-Irvine, Irvine, California, USA.
Geidy E SerranoBanner Sun Health Research Institute, Sun City, Arizona, USA.
Thomas G BeachBanner Sun Health Research Institute, Sun City, Arizona, USA.
Jogeshwar MukherjeeDepartment of Radiological Sciences, Preclinical Imaging, University of California-Irvine, Irvine, California, USA.ORCID 0000-0003-1009-877X

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI RICHARD A. VAN ETTEN · 1994 to 2026
$57.9M
Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI HEATHER Allyson BIMONTE-NELSON · 2021 to 2026
$24.9M
National Brain and Tissue Resource for Parkinson's Disease and Related DisordersU24NS072026 · NINDS · BANNER SUN HEALTH RESEARCH INSTITUTE · PI BEACH, THOMAS G · 2011 to 2015
$7.8M
PET Imaging Agents for Nicotinic a4b2 ReceptorsR01AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2007 to 2017
$2.6M
PET Imaging agents for a4b2 Nicotinic ReceptorsRF1AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHRISTIAN, BRADLEY T, MUKHERJEE, JOGESHWAR · 2019 to 2020
$2.2M
Novel Tau-Targeted Radiohalogenated Agents for Alzheimer's DiseaseR01AG077700 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Jogeshwar Mukherjee · 2024 to 2026
$2.1M
Evaluation of Monoamine Oxidase-A as a New Biomarker for Alzheimer's DiseaseR21AG079189 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2022 to 2022
$432k
NCI NIH HHS P30 CA062203NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG029479NIA NIH HHS R01 AG077700NIA NIH HHS R21 AG079189NIA NIH HHS RF1 AG029479NIH HHS AG077700NINDS NIH HHS U24 NS072026
6 · The paper itself

Abstract

Alzheimer's disease (AD) is characterized by the accumulation of tau tangles that aggregate into neurofibrillary tangles (NFT). This study aims to assess binding of [

Indexed as

Alzheimer DiseaseHippocampustau ProteinsAgedAged, 80 and overCarbolinesDyrk KinasesFemaleHarmineHumansIodine RadioisotopesMaleMiddle AgedMonoamine OxidaseMonoamine Oxidase InhibitorsProtein Serine-Threonine Kinases7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinesDyrk KinasesHarmineIodine-125Iodine RadioisotopesMonoamine OxidaseMonoamine Oxidase InhibitorsProtein Serine-Threonine KinasesProtein-Tyrosine Kinasestau Proteins[125I]IPPIAlzheimer's diseaseharminehippocampushuman tauMK‐6240

Identifiers

PMID40619690
PMCPMC12230280

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.