Evidence map›Paper›PMID 40619895›Full record

ArticleBJPsych open2025

Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar individuals and healthy controls.

Heidi Ka Ying Lo, Roger S McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys and 1 more

Abstract read
In one paragraph

Article in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heidi Ka Ying LoDepartment of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0003-2551-5230
Roger S McIntyreDepartment of Psychiatry, University of Toronto, Canada.ORCID https://orcid.org/0000-0003-4733-2523
Iris Wai Tung TsuiDepartment of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.
Fiona Yan Yee HoDepartment of Psychology, The Chinese University of Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0001-7448-4982
Ting Kin NgDepartment of Psychology, Lingnan University, Hong Kong.ORCID https://orcid.org/0000-0001-9578-5215
Corine Sau Man WongSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0003-3363-1004
Suet Ying YuenDepartment of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.
Chit Tat LeeDepartment of Psychiatry, Queen Mary Hospital, Hong Kong.
Chun Yin PoonDepartment of Psychology, The Chinese University of Hong Kong, Hong Kong.
Inez Myin-GermeysCenter of Contextual Psychiatry, Department of Neurosciences, KU Leuven, Belgium.
Ka Fai ChungDepartment of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnostic accuracy is an unmet need for major depressive disorder (MDD) and major depressive episode (MDE) in bipolar disorder. Very limited research has evaluated bipolar disorder/MDE and MDD using ecological momentary assessment (EMA) time-series data.

aimsWe aimed to examine differentiating phenomenological characteristics in positive affect dynamics, and temporal relationships with pleasure towards current activity and meaning in life (MIL), among MDD, MDE/bipolar disorder and healthy controls using EMA.

methodParticipants (

resultsFrom 4632 EMA observations, positive affect dynamics (inertia, variability and instability) did not differ significantly across groups (all

conclusionIndividuals with MDE/bipolar disorder, but not MDD, had less self-reported MIL from positive affect and pleasure. There is little evidence that emotional experience alone characterises the pathophysiology between MDD and MDE/bipolar disorder; such investigation may be limited by within-group heterogeneity. Our findings provide a new perspective on using a time-series approach beyond bimodal measures in EMA to differentiate bipolar disorder/MDE and MDD.

Indexed as

anhedoniabipolar disorderdepressionecological momentary assessment (EMA)Experience sampling method (ESM)

Identifiers

PMID40619895
PMCPMC12247073

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.