Evidence map›Paper›PMID 40620012›Full record

ArticleTurkish journal of orthodontics2025

The Effect of Diabetes Mellitus on Mandibular Growth.

Nearchos Panayi, Apostolos Tsolakis, Dimitrios Konstantonis, Ioannis Tsolakis, Maria Kouri, Georgia Kotantoula, Ismene A Dontas

Abstract read
In one paragraph

Article in Turkish journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nearchos PanayiEuropean University Cyprus Faculty of Dentistry, Department of Orthodontics, Nicosia, Cyprus.ORCID 0000-0003-0025-9971
Apostolos TsolakisNational and Kapodistrian University of Athens Faculty of Dentistry, Department of Orthodontics, Athens, Greece.ORCID 0000-0003-3019-5438
Dimitrios KonstantonisNational and Kapodistrian University of Athens Faculty of Dentistry, Department of Orthodontics, Athens, Greece.ORCID 0000-0002-4522-5567
Ioannis TsolakisAristotle University of Thessaloniki, Faculty of Health Sciences, Department of Dentistry, Thessaloniki, Greece.ORCID 0000-0002-5435-4889
Maria KouriNational and Kapodistrian University of Athens Faculty of Dentistry, Department of Orthodontics, Athens, Greece.ORCID 0000-0002-0009-4911
Georgia KotantoulaNational and Kapodistrian University of Athens Faculty of Dentistry, Department of Orthodontics, Athens, Greece.ORCID 0000-0002-3322-9974
Ismene A DontasNational and Kapodistrian University of Athens Faculty of Medicine, Laboratory for Research of the Musculoskeletal System, Attica, Greece.ORCID 0000-0002-2440-0119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is a chronic condition characterized by insufficient insulin production or utilization. Affecting approximately 8.5% of adults globally, diabetes is categorized primarily into Type 1, Type 2, and gestational diabetes. Diabetes markedly impacts bone health, particularly affecting the growth and development of the mandible. Key alterations include impaired bone metabolism leading to diminished bone density and strength. Additionally, diabetes impairs bone healing processes, often exacerbated by deficiencies in vitamin D, thus increasing fracture risks. Understanding the interplay between diabetes and mandibular growth is essential for effective dental treatment planning and patient management. Importantly, the condition also alters essential growth factors and local blood supply to the mandibular region, compromising overall growth. Impaired bone healing and formation also affects orthodontic treatment in diabetic patients. Future research should prioritize longitudinal studies examining diabetes's long-term impact on mandibular development, exploring genetic predispositions and biomechanical properties. Understanding these mechanisms will facilitate more effective clinical strategies to mitigate the adverse effects of diabetes on bone health and optimize patient outcomes.

Indexed as

bone densitybone metabolismbone strengthclinical strategiesDiabetes mellitusgenetic predispositionhealingmandibular growth

Identifiers

PMID40620012
PMCPMC12236124

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.