ArticleFrontiers in medicine2025
The impact of perivascular adipose tissue characteristics on incident cardiovascular events in non-dialysis chronic kidney disease patients.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Epicardial adipose tissue: an overtly concealed contributor to cardiovascular events in chronic kidney disease patients.Lipids in health and disease · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Patients with chronic kidney disease (CKD) face a high risk of developing cardiovascular disease. However, the relationship between perivascular adipose tissue characteristics and incident cardiovascular outcomes in non-dialysis patients with CKD remains unclear. Methods: This was prospective, observational, cohort study. A total of 220 CKD patients (stages G2-G5) without prior cardiovascular disease were enrolled. Attenuations and volumes of peri-coronary adipose tissue (PCAT), thoracic peri-aortic adipose tissue (TAT), and epicardial adipose tissue (EAT) were measured by ECG-gated non-enhanced computed tomography scans. Total coronary artery (CAC) and thoracic aorta calcification (TAC) were quantified with Agatston scores. Results: Lower estimated glomerular filtration rate (eGFR) was associated with higher attenuation of PCAT, TAT, and EAT, but volumes differences across eGFR tertile were not significant. Multivariate analysis indicated that age and body mass index (BMI) were independently associated with PCAT, TAT, and EAT volumes. Smoking and serum phosphorus levels correlated with PCAT attenuation, while proteinuria, BMI, HDL cholesterol, and white blood cell counts were linked to TAT attenuation. EAT attenuations was associated with age, serum creatinine, proteinuria, BMI, smoking, and systolic blood pressure. During a median follow-up of 26.56 months, 23 patients developed cardiovascular events, with high EAT volume (≥129.14 cm Conclusion: These findings suggest EAT volume significantly predicts incident cardiovascular events in non-dialysis CKD patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.