Evidence map›Paper›PMID 40620568›Full record

ArticleFrontiers in public health2025

Prevalence and factors associated with mental health challenges among adolescents with HIV and viral non-suppression in rural northern Uganda.

Jeremiah Mutinye Kwesiga, Justine Diana Namuli, Benedict Akimana, Joyce Nalugya Serunjogi, Sabrina Bakeera Kitaka, Musisi Seggane, Pontiano Kaleebu, Moffat Nyirenda, Etheldreda Nakimuli-Mpungu

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeremiah Mutinye KwesigaMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.
Justine Diana NamuliDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Benedict AkimanaButabika National Referral Mental Hospital, Ministry of Health of Uganda, Kampala, Uganda.
Joyce Nalugya SerunjogiDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Sabrina Bakeera KitakaDepartment of Pediatrics, College of Health Sciences, Makerere University, Kampala, Uganda.
Musisi SegganeDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Pontiano KaleebuMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.
Moffat NyirendaMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.
Etheldreda Nakimuli-MpunguMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Adolescents living with HIV (ALWH) face significant mental health challenges, such as depression and anxiety, which negatively impact their HIV treatment outcomes. This study investigated the prevalence and factors associated with mental health challenges among adolescents with unsuppressed viral loads in Northern Uganda. Methods: In 2021, 121 dyads of caregivers and ALWH (10 to 18 years) with unsuppressed viral loads were recruited from five community-based HIV clinics in Kitgum district. They were assessed for mental health challenges using the Revised Child Anxiety and Depression Scale (RCADS-25), the Patterson Suicide Risk Assessment Tool and the Clinician-administered Post-traumatic Stress Disorder Scale for Children and Adolescents (CAPS-CA). Bivariate and multivariate analysis of the data was carried out using STATA version 18. Results: Emotional problems were observed in 61.97% of participants. Among these, depression was present in 45.45% of individuals, and all participants diagnosed with depression also exhibited significant comorbid anxiety symptoms. Notably, 16.52% of participants experienced anxiety without comorbid depression. Having food security (OR = 0.03; Conclusion: These results emphasize the importance of addressing underlying socio-economic and psychological factors to improve mental health well-being. Targeted interventions focused on reducing barriers to resources and providing mental health support are essential for fostering equitable mental health outcomes.

Indexed as

AnxietyDepressionHIV InfectionsMental HealthRural PopulationAdolescentChildFemaleHumansMalePrevalenceUgandaViral LoadadolescentsanxietydepressionHIVUgandaunsuppressed viral load

Identifiers

PMID40620568
PMCPMC12226497

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.