Evidence map›Paper›PMID 40620682›Full record

ReviewInternational journal of nanomedicine2025

Medicinal Plant-Derived Exosome-Like Nanovesicles as Regulatory Mediators in Microenvironment for Disease Treatment.

Zhiying Feng, Jiawang Huang, Jingmin Fu, Lixin Li, Rong Yu, Ling Li

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Food science & nutrition · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Protective Effects of Orally AdministeredInternational journal of nanomedicine · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiying Feng *College of Traditional Chinese Medicine of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People's Republic of China.ORCID 0009-0000-9125-4687
Jiawang Huang *College of Traditional Chinese Medicine of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People's Republic of China.
Jingmin FuCollege of Traditional Chinese Medicine of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People's Republic of China.
Lixin LiCollege of Medicine of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People's Republic of China.
Rong YuCollege of Traditional Chinese Medicine of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People's Republic of China.ORCID 0009-0005-0840-2797
Ling LiCollege of Integrated Traditional Chinese and Western Medicine of Hunan University of Chinese Medicine, Hunan, Changsha, 410208, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plant-derived exosome-like nanovesicles is a kind of vesicles with a diameter of 30-300 nm extracted from medicinal plants, which can regulate the microenvironment of various systems, diseases and cells through multiple drug delivery routes, so as to achieve the purpose of alleviating and treating diseases. In this paper, the extraction and identification methods of nanovesicles derived from medicinal plants were summarized. Then, according to the systematic classification of diseases, the effects and mechanisms of the treatment of diseases and the regulation of the microenvironment by the nanovesicles derived from medicinal plants were summarized and analyzed. This paper finds Medicinal plant-derived exosome-like nanovesicles, as plant-derived nanoscale vesicles, can act more efficiently on various microenvironments of the body such as inflammation, tumors, immunity and the intestine through various administration methods such as oral administration and intravenous injection according to the characteristics of the disease, achieving the effect of treating diseases and alleviating symptoms. Medicinal plant-derived exosome-like nanovesicles have initiated a new model of transboundary communication regulation involving plants in the human microenvironment, using their own advantages to regulate the human microenvironment. Meanwhile, it can also be used as a drug carrier to achieve a dual communication regulation effect. It provides ideas for the follow-up research and clinical use of nanovesicles derived from medicinal plants.

Indexed as

ExosomesNanoparticlesPlants, MedicinalAnimalsDrug CarriersDrug Delivery SystemsHumansNeoplasmsTumor MicroenvironmentDrug Carriersmedicinal plantsmicroenvironmentnanovesiclessystemic disease mechanism

Identifiers

PMID40620682
PMCPMC12227098

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.