Evidence map›Paper›PMID 40620685›Full record

ReviewInternational journal of nanomedicine2025

Biological and Bioinspired Vesicles for Wound Healing: Insights, Advances and Challenges.

Yingchao Zhao, Tingrui Zhang, Guanlin Zhao, Jiaye Lu, Xinyue Zhang, Yongxian Lai, Zhongjian Chen, Xiaofeng Ding, Zongguang Tai

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yingchao Zhao *Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Tingrui Zhang *Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Guanlin Zhao *Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200070, People's Republic of China.
Jiaye LuShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Xinyue ZhangShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Yongxian LaiShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Zhongjian ChenShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.ORCID 0000-0003-3789-7096
Xiaofeng DingShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.
Zongguang TaiShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, People's Republic of China.ORCID 0000-0001-5603-745X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Millions of people suffer traumatic injuries and surgical procedures each year, making effective wound management very important. Benign wound repair is essential for structural and functional recovery of damaged tissues. Natural biological vesicles have emerged as attractive candidates for accelerating wound healing due to their endogenous nature and distinctive biological properties. However, obstacles such as low separation yields, potential safety concerns, and unsatisfactory production restrict their continuous application. In recent years, bioinspired materials and technologies have played an important role in the field of remodeling wound healing. Bioinspired vesicles function by effectively transporting therapeutic substances through mimicking the chemical and biological properties in nature, and can be modified and prepared through a variety of advanced techniques such as genetic engineering, chemical modification, and physical techniques, and are good substitutes for natural vesicles. Therefore, integrating bioinspired design into vesicles to promote wound healing can improve the curative effect while maintaining good safety, which helps to accelerate the clinical transformation of vesicles. This review discusses the latest progress, barriers to clinical transformation, and future development directions of biological and bioinspired vesicles for wound healing.

Indexed as

Biomimetic MaterialsWound HealingAnimalsDrug Delivery SystemsHumansbioinspired vesiclesbiological vesiclesextracellular vesiclespreparationwound healing

Identifiers

PMID40620685
PMCPMC12227003

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.