Evidence map›Paper›PMID 40622387›Full record

ArticleeLife2025

Heat stress induces phage tolerance in

Fan Zhang, Hao-Ze Chen, Bo Zheng, Liang Huang, Ye Xiang, Jing-Ren Zhang, Jia-Feng Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fan ZhangCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0009-0001-1425-8112
Hao-Ze ChenCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0009-0007-9269-3025
Bo ZhengCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0000-0003-3911-7217
Liang HuangCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0000-0001-8414-7883
Ye XiangCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0000-0003-0230-9522
Jing-Ren ZhangCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0000-0003-4973-4243
Jia-Feng LiuCenter for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.ORCID https://orcid.org/0000-0003-3301-7194

Funding

National Key Research and Development Program of China 2022YFC2303202Tsinghua University Dushi program 20231080044Tsing-Pekin Joint Center for Life Sciences 20111770319
6 · The paper itself

Abstract

Antibiotic resistance and tolerance present significant challenges in global healthcare, necessitating alternative strategies such as phage therapy. However, the rapid emergence of phage-resistant mutants poses a potential risk. Here, using

Indexed as

BacteriophagesHeat-Shock ResponseKlebsiella pneumoniaeAnti-Bacterial AgentsHot TemperatureAnti-Bacterial Agentsheat stresshost-phage interactioninfectious diseaseKlebsiella pneumoniaemicrobiologyphagesphage tolerance

Identifiers

PMID40622387
PMCPMC12234005

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.