Evidence map›Paper›PMID 40623645›Full record

ArticleJournal of affective disorders2025

Sociodemographic and clinical factors associated with use of depression treatment among people with HIV in the United States: An electronic health records-based cohort study.

Verena E Metz, Andrea H Kline-Simon, Tory Levine, Varada Sarovar, Alexandra Lea, Natalia Van Doren, Stacy A Sterling, Michael J Silverberg, Derek D Satre

Abstract read
In one paragraph

Article in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Advances in Treatment of Psychiatric Disorders in Patients with HIV.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Verena E MetzKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America. Electronic address: verena.e.metz@kp.org.
Andrea H Kline-SimonKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.
Tory LevineKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.
Varada SarovarKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.
Alexandra LeaKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.
Natalia Van DorenKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, United States of America.
Stacy A SterlingKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, United States of America.
Michael J SilverbergKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.
Derek D SatreKaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, United States of America.

Funding

Substance Use Disorders Treatment/Services Research Training ProgramT32DA007250 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre, Janice Y Tsoh · 1991 to 2026
$7.4M
2/3 COMpAAAS Tripartite: ART-CC, KP, and VAU01AA026230 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI SATRE, DEREK D, SILVERBERG, MICHAEL J · 2017 to 2021
$3.0M
Mentoring alcohol use intervention research in HIV health care settingsK24AA025703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre · 2018 to 2026
$1.8M
NIAAA NIH HHS K24 AA025703NIAAA NIH HHS U01 AA026230NIDA NIH HHS T32 DA007250
6 · The paper itself

Abstract

backgroundDepression is highly prevalent among people with HIV (PWH), and treatment is critical. We examined associations between sociodemographic and clinical characteristics, focusing on alcohol use and smoking, with use of depression treatment.

methodsElectronic health record data from an integrated healthcare system in Northern California were used to identify PWH who had a primary care visit (index) between 1/1/2014-12/31/2020 and a depression diagnosis within 6 months of the index date. Outcomes included separate indicators for outpatient mental health (MH) encounters and antidepressant prescription fills in the year post index.

resultsAmong 3078 PWH, 24.7 % (761) had a depression diagnosis; of those, 52.6 % were aged 50+, 10.5 % female, 56.1 % White, 36.4 % reported alcohol use in the past 3 months and 18.7 % reported current smoking. Seventy-six percent used depression treatment services (antidepressants [68 %] and outpatient MH [35 %]). Patients aged 50-59 years (OR = 0.52, CI = 0.34, 0.80) and 60+ years (OR = 0.27, CI = 0.14, 0.50) were less likely to have outpatient MH encounters compared to patients ≤40 years. Compared to White patients, Black (OR = 0.37, CI = 0.23, 0.59) and Hispanic (OR = 0.48, CI = 0.31, 0.75) patients were less likely to have antidepressant prescription fills, and Black (OR = 0.47, CI = 0.28, 0.77), Hispanic (OR = 0.58, CI = 0.35, 0.94) and Asian (OR = 0.48, CI = 0.25, 0.93) patients were less likely to use any depression treatment. Neither alcohol use nor smoking were associated with depression treatment.

conclusionsWe found substantial demographic disparities in use of depression treatment services among PWH and depression. Facilitating access to mental health care for older and racial and ethnic minority patients should be prioritized.

Indexed as

Antidepressive AgentsDepressionDepressive DisorderHIV InfectionsAdultAgedCaliforniaCohort StudiesElectronic Health RecordsFemaleHumansMaleMiddle AgedSmokingSociodemographic FactorsUnited StatesAntidepressive AgentsAgingAlcohol useDepressionHIVOlder AdultsRace and ethnicitySmokingTreatment

Identifiers

PMID40623645
PMCPMC12323731

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.