ArticleScientific reports2025
Association between phthalates exposure and urine flow rate.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Phthalate exposure and its impact on mental health risk in the elderly Thai population.Discover mental health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to examine the association between phthalate exposure and urine flow rate (UFR). Data from 6951 adult participants across five consecutive NHANES cycles (2009-2018) were analyzed. High-performance liquid chromatography-electrospray ionization tandem mass spectrometry was used to measure urinary concentrations of 10 highly detectable phthalate metabolites (PMs). Associations between PMs and UFR were investigated using various analytical approaches, including weighted linear regression, weighted quantile sum regression (WQS), quantile g-computation (qgcomp), restricted cubic spline (RCS), and Bayesian kernel-machine regression (BKMR) models. Each quartile increase in the WQS index for PM mixtures was associated with a - 0.042 lower ln-transformed UFR (95% CI - 0.07, - 0.014). The qgcomp regression model yielded consistent results. In BKMR analysis, PM mixtures showed a significant negative association with ln-transformed UFR, with mono-2-ethyl-5-carboxypentyl phthalate (MECPP) and mono-benzyl phthalate (MBzP) identified as potential key contributors. In addition, the RCS results showed an inverted s-type nonlinear relationship between MECPP and MBzP, and UFR. Exposure to phthalates is associated with lower UFR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.