Evidence map›Paper›PMID 40624253›Full record

ArticleScientific reports2025

Biochemical and psychological markers of fatigue and recovery in mixed martial arts athletes during strength and conditioning training.

Joanna Ostapiuk-Karolczuk, Hanna Dziewiecka, Patryk Bojsa, Mirosława Cieślicka, Monika Zawadka-Kunikowska, Kaźmierczak Wojciech, Anna Kasperska

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
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  6. Physiological Responder Profiles and Fatigue Dynamics in Prolonged Cycling.Journal of functional morphology and kinesiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joanna Ostapiuk-KarolczukDepartment of Biological Sciences, Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow Wielkopolski, Estkowskiego 13, Gorzów Wielkopolski, 66-400, Poland. j.ostapiuk@awf-gorzow.edu.pl.ORCID http://orcid.org/0000-0003-4214-1488
Hanna DziewieckaDepartment of Biological Sciences, Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow Wielkopolski, Estkowskiego 13, Gorzów Wielkopolski, 66-400, Poland.ORCID http://orcid.org/0000-0002-9450-6832
Patryk BojsaDepartment of Biological Sciences, Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow Wielkopolski, Estkowskiego 13, Gorzów Wielkopolski, 66-400, Poland.ORCID http://orcid.org/0009-0006-8512-7044
Mirosława CieślickaDepartment of Human Physiology, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Karłowicza 24, Bydgoszcz, 85-092, Poland.ORCID http://orcid.org/0000-0002-0407-2592
Monika Zawadka-KunikowskaDepartment of Human Physiology, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Karłowicza 24, Bydgoszcz, 85-092, Poland.ORCID http://orcid.org/0000-0003-3861-7113
Kaźmierczak WojciechDepartment of Human Physiology, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Karłowicza 24, Bydgoszcz, 85-092, Poland.ORCID http://orcid.org/0000-0001-8176-1802
Anna KasperskaDepartment of Biological Sciences, Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow Wielkopolski, Estkowskiego 13, Gorzów Wielkopolski, 66-400, Poland.ORCID http://orcid.org/0000-0002-8187-5436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed martial arts (MMA) training imposes significant physiological and psychological demands, increasing the risk of overtraining. This study aimed to assess temporal changes in biochemical and psychological fatigue and recovery markers during a structured 3-week strength and conditioning training program in professional MMA athletes. Ten male MMA athletes (26.2 ± 0.9 years; 7.0 ± 2.0 years of training experience) participated. Blood samples and psychological assessments (Profile of Mood States - POMS) were collected at four time points: pre-training (T-0), and after each training week (T-1, T-2, T-3). Analyzed biomarkers included cortisol, testosterone, catecholamines, hs-CRP, creatine kinase, and metabolic markers. Data were analyzed using repeated measures statistical tests to assess time-dependent changes. Cortisol and hs-CRP increased significantly after the first week (p < 0.01), while testosterone and catecholamines remained stable. Creatine kinase showed a persistent rise (p < 0.01), indicating muscle damage. Psychological assessments revealed increased fatigue, tension, and confusion, with reduced vigor (p < 0.05). Despite biochemical markers partially recovering, subjective fatigue persisted, highlighting a disconnect between physiological and psychological recovery. These findings highlight the importance of integrated monitoring strategies that include both biochemical and psychological assessments. The divergence between physiological and psychological recovery underscores the complexity of athlete fatigue and the need for integrated recovery interventions. Future research should explore long-term adaptations, sex-based differences, and targeted recovery strategies to optimize training, performance, and well-being in MMA athletes.

Indexed as

AthletesBiomarkersFatigueMartial ArtsResistance TrainingAdultCatecholaminesCreatine KinaseHumansHydrocortisoneMaleTestosteroneYoung AdultBiomarkersCatecholaminesCreatine KinaseHydrocortisoneTestosteroneFatigueHormonesInflammationMMA athletesMood states

Identifiers

PMID40624253
PMCPMC12234679

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.