Evidence mapPaperPMID 40625367Full record

ArticleInternational journal of women's health2025

Optimizing Pregnancy Outcomes: The Role of Gynecologists in Preconceptional Care in Italy.

Herbert Valensise, Cristina Banzi, Cecilia Bonin, Marinella Dell'Avanzo, Nicoletta Di Simone, Daniele Farsetti, Francesca Manganello, Federico Mecacci, Caterina Serena, Barbara Villaccio and 1 more

Abstract read
In one paragraph

Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Herbert ValensiseDepartment of Surgical Sciences, Tor Vergata University, Rome, Italy.
Cristina BanziUniversity Hospital of Ferrara, Ferrara, Italy.
Cecilia BoninUniversity of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
Marinella Dell'AvanzoHumanitas San Pio X, Milan, Italy.
Nicoletta Di SimoneIRCCS Humanitas Research Hospital, Milan, Italy.
Daniele FarsettiDepartment of Surgical Sciences, Tor Vergata University, Rome, Italy.ORCID 0000-0002-4419-659X
Francesca ManganelloPrivate Practice, Venezia, Italy.
Federico MecacciDepartment of Experimental, Clinical and Biomedical Sciences, Obstetrics and Gynecology Unit, Careggi University Hospital, Florence, Italy.
Caterina SerenaDepartment of Experimental, Clinical and Biomedical Sciences, Obstetrics and Gynecology Unit, Careggi University Hospital, Florence, Italy.
Barbara VillaccioSan Pietro Fatebenefratelli Hospital, Rome, Italy.
Elsa VioraItalian Society of Obstetrics and Gynecology (SIGO), Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The preconceptional period is crucial for women and couples who desire children as it influences the progress and outcomes of a healthy pregnancy. Preconceptional care is now an accepted paradigm by most healthcare professionals. However, its implementation in healthcare programs is still in the early stages. Preconceptional care starts with communication and a collection of personal and family medical history. It then encompasses a variety of recommendations for lifestyle interventions, as well as preventive laboratory tests. This review will summarize current recommended procedures, from nutritional to disease screening, and their impact on pregnancy outcomes. Folic acid supplementation has been shown to significantly decrease complications such as neural tube defects, and is now widely recommended during the preconceptional phase. Additionally, nutritional supplementation, including the intake of vitamins D and B12, has been linked to healthier pregnancies. Screening for ToRCH infections (toxoplasmosis, syphilis, hepatitis B, rubella, cytomegalovirus, and herpes simplex virus), as well as non-infectious conditions, may help avoid complications during pregnancy. This review will also provide an overview of current practices worldwide, focusing on the Italian context. This document will be helpful to update the medical community, especially gynecologists, on the current knowledge of the benefits of 1) maintaining a healthy nutritional state, including vitamin and mineral supplementation, 2) screening strategies for infectious and non-infectious diseases, and 3) avoiding dangerous behaviors, such as smoking, alcohol consumption, and drug use, for women and couples planning a pregnancy. It also provides suggestions on how to identify such couples to best intervene during the "window of opportunity". Finally, we aim to provide a simple decalogue, which healthcare professionals can use as a checklist. It can also be delivered directly to women or couples planning a pregnancy, reaching them with straightforward language.

Indexed as

disease screeninggenetic screeningrecommendationssupplementswoman’s health

Identifiers

PMID40625367
PMCPMC12230326

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.