ArticleFrontiers in psychology2025
Longitudinal study of socio-emotional cognitive processing in individuals with anorexia nervosa and the impact of autistic characteristics on neural processing.
Article in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Difficulties in socio-emotional cognitive processing are a key feature in individuals with anorexia nervosa (AN); however, the underlying neural processing, particularly longitudinal, is poorly understood. Compounding difficulties is the presence of overrepresented autistic characteristics, and it is unclear how these impact socio-emotional cognitive neural processing in individuals with AN. Method: A total of 92 participants, including 65 individuals with AN and 27 controls, took part in a longitudinal assessment at two time points, approximately 2 years apart, by undertaking socio-emotional cognitive tasks while undergoing functional magnetic resonance imaging (fMRI). A multivariate approach was used to predict autistic characteristics from generated maps from the AN group. Results: A group-by-time interaction effect was demonstrated in several brain regions in response to tasks, with the regions with the strongest evidence being the right frontal operculum/pole. The multivariate approach revealed a wide distribution of brain regions contributing to autistic characteristics. Conclusion: Neural changes over time in the right frontal operculum/pole potentially represent a compensatory mechanism for cognitive difficulties. Autistic characteristics in individuals with AN are instantiated and impact a wide distribution of neural regions, particularly during socio-emotional cognitive processing.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.