Evidence map›Paper›PMID 40626640›Full record

ReviewDevelopment (Cambridge, England)2025

Development and diversity of astrocytes.

Michael R Williamson, Sanjana Murali, Benjamin Deneen

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael R WilliamsonCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-8049-4463
Sanjana MuraliCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Benjamin DeneenCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-6335-1081

Funding

Astrocyte Transcriptional Dependencies in Brain CircuitsR35NS132230 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI Benjamin Deneen · 2023 to 2026
$3.5M
Macrophage functional dynamics in adult heart regenerationR01HL164933 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Jiandong Liu · 2023 to 2026
$2.4M
Defining Roles for Astrocyte Subpopulations in the Aging BrainR01AG071687 · NIA · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN · 2021 to 2025
$2.0M
Defining Astrocyte Engram Ensembles During Memory FormationR21MH134002 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN · 2023 to 2023
$440k
American Heart Association 25POST1363224National Institutes of Health Funder R01-AG071687National Institutes of Health Funder R01HL164933National Institutes of Health Funder R21-MH134002NHLBI NIH HHS R01 HL164933NIA NIH HHS R01 AG071687NIMH NIH HHS R21 MH134002NINDS NIH HHS R35 NS132230
6 · The paper itself

Abstract

Proper development of the central nervous system (CNS) depends on astrocytes, which are the most abundant glial cells in the CNS. Here, we provide an overview of astrocyte ontogeny and morphogenesis, highlighting mechanisms that regulate astrocyte development. In addition, we describe the roles of astrocytes in regulating the development of other CNS cell types, with emphasis on neural circuits and vascular networks. We also discuss evidence for astrocyte diversity and its implications for CNS development. Finally, we pose open questions related to astrocyte development and its intersection with astrocyte diversity.

Indexed as

AstrocytesCentral Nervous SystemAnimalsCell DifferentiationHumansAstrocyteCell diversityCNS development

Identifiers

PMID40626640
PMCPMC12276804

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.