Evidence map›Paper›PMID 40627430›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

Acute effect of a multi-ingredient pre-workout supplement on pacing and kinetic expression during shorter and longer bouts of high intensity functional training.

Gerald T Mangine, Christopher Staples, James W Henley, Ashley Hines, Kristyn C McGeehan, Wysmark Chaves, Wil King, Tiffany A Esmat, John R McLester, Jacob L Grazer

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gerald T MangineKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.ORCID 0000-0003-2718-2564
Christopher StaplesKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
James W HenleyKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Ashley HinesKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Kristyn C McGeehanKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Wysmark ChavesKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Wil KingKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Tiffany A EsmatKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
John R McLesterKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.
Jacob L GrazerKennesaw State University, Exercise Science and Sport Management, Kennesaw, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-intensity functional training (HIFT) varies daily workout programming, and trainees are often tasked with completing "as many repetitions as possible" (AMRAP) within a set time. Successful performance depends on fatigue management skills and maintaining a consistent expression of force and velocity when performing and transitioning between exercises over the duration of the workout. Multi-ingredient pre-workout (MIPS) supplement formulations often contain ingredients shown to facilitate energy availability and mitigate fatigue, and therefore, might positively affect HIFT performance. This study aimed to assess a multi-ingredient pre-workout supplement's acute effect on pacing and the expression of kinetics throughout a 5- and 15-minute HIFT-style AMRAP.

methodsTwelve men and 10 women (29.3 ± 7.1 years, 171 ± 7 cm, 80.5 ± 15.6 kg) with HIFT experience ( > 2 years) completed four weekly visits, consuming either the supplement (S) or placebo (P) before a 5- or 15-minute AMRAP of rowing (9 or 7 Calories for men and women), six barbell thrusters (43.1 kg and 29.5 kg), and three jumps onto a box (0.61 m and 0.51 m). Video recordings of each workout were analyzed to quantify repetitions completed, volume load (kg), and pace (i.e. time spent on each workout component, repetition completion rate). The expression of kinetics and related factors were quantified during rowing via the ergometer microcomputer (Calories per stroke, power [W], and strokes per minute), during barbell thrusters by a 3D motion tracking system (barbell velocity [m · sec

resultsMen and women completed a greater total volume load (~4.4%,

conclusionsAlthough it did not affect repetitions completed, the multi-ingredient pre-workout supplement led to a greater volume load and faster overall repetition completion rate. These were primarily due to improvements surrounding rowing performance and evidence of an effect on thruster pacing and box jump force expression. The effects were similar in both sexes and workout durations. Athletes might consider this MIPS formulation to improve HIFT performance, particularly when a workout contains a component that requires sustained, continuous effort.

Indexed as

Athletic PerformanceDietary SupplementsHigh-Intensity Interval TrainingPhysical Conditioning, HumanSports Nutritional Physiological PhenomenaAdultFatigueFemaleHumansKineticsMaleMuscle FatigueWater SportsYoung AdultAMRAPCrossFit®forceHIFTpowerrepetition completion rate

Identifiers

PMID40627430
PMCPMC12239229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.