Evidence map›Paper›PMID 40627828›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Telomere Dysfunction in Renal Tubular Epithelial Cells Leads to Kidney Fibrosis.

Sarita Saraswati, Paula Martínez, Rosa Serrano, Diego Mejías, Osvaldo Graña-Castro, Ruth Álvarez Díaz, Juana María Flores, Maria A Blasco

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarita SaraswatiTelomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Paula MartínezTelomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Rosa SerranoTelomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Diego MejíasConfocal Microscopy Unit, Biotechnology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.ORCID 0000-0003-0755-0518
Osvaldo Graña-CastroBioinformatics Unit, Structural Biology and Biocomputing Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.ORCID 0000-0003-1615-4242
Ruth Álvarez DíazBioinformatics Unit, Structural Biology and Biocomputing Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.ORCID 0000-0003-0141-4881
Juana María FloresAnimal Surgery and Medicine Department, Faculty of Veterinary Science, Complutense University of Madrid, Madrid, Spain.ORCID 0000-0002-7995-4426
Maria A BlascoTelomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.ORCID 0000-0002-4211-233

Funding

Comunidad de Madrid S2017/BMD-3770H2020 European Research Council SHELTERINS GA882385World Cancer Research Fund 16-1177
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKICKDinterstitial fibrosisrenal epithelial cellrenal fibrosisrenal tubular epithelial cellssignalingtransgenic mouse

Identifiers

PMID40627828
PMCPMC12677824

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.