Evidence map›Paper›PMID 40628293›Full record

ReviewOpen biology2025

The Slit-Robo signalling pathway in nervous system development: a comparative perspective from vertebrates and invertebrates.

Nicole Sanhueza, Evelyn C Avilés, Carlos Oliva

Abstract readReview
In one paragraph

Review in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Myotendinous Junction development and repair.Journal of orthopaedic translation · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole SanhuezaFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Metropolitan Region 8331150, Chile.
Evelyn C AvilésFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Metropolitan Region 8331150, Chile.
Carlos OlivaFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Metropolitan Region 8331150, Chile.ORCID 0000-0002-9551-149X

Funding

Agencia Nacional de Investigación y Desarrollo
6 · The paper itself

Abstract

During nervous system development, growing axons find their targets with the help of guidance cues. These cues, which can be secreted molecules provided by neighbouring cells or transmembrane proteins mediating cell-cell contacts with the growing axons, act as either chemoattractants or chemorepellents. Over the last decades, several axon guidance molecules have been identified. One of the classical guidance cues is the Slit protein. Slit is a secreted protein, initially identified in a genetic screen in the fruit fly

Indexed as

InvertebratesNerve Tissue ProteinsNervous SystemReceptors, ImmunologicSignal TransductionVertebratesAnimalsAxonsDrosophila ProteinsHumansRoundabout ProteinsDrosophila ProteinsNerve Tissue ProteinsReceptors, ImmunologicRoundabout Proteinsaxonal guidanceneuronal developmentSlit–Robo signalling

Identifiers

PMID40628293
PMCPMC12308364

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.