Evidence mapPaperPMID 40628835Full record

Trial reportScientific reports2025

Pharmacokinetic evaluation of two oral Resveratrol formulations in a randomized, open-label, crossover study in healthy fasting subjects.

Jing Wang, Tingting Liu, Peiru Chen, Dongli Yin, Haijun Zhang, Xiang Qiu, Shengcan Zou, Weiyong Li

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Targeting the OXNAD1-PTGS2 axis with resveratrol overcomes ferroptosis Inhibition and reverses 5-FU resistance in gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Anti-Inflammatory Properties of Resveratrol.International journal of molecular sciences · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jing Wang *Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Tingting Liu *Qingdao Chenland Pharmaceutical Co., Ltd, Qingdao, China.
Peiru ChenDepartment of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Dongli YinQingdao Chenland Pharmaceutical Co., Ltd, Qingdao, China.
Haijun ZhangQingdao Chenland Pharmaceutical Co., Ltd, Qingdao, China.
Xiang QiuQingdao Chenland Pharmaceutical Co., Ltd, Qingdao, China.
Shengcan ZouQingdao Chenland Pharmaceutical Co., Ltd, Qingdao, China.
Weiyong LiDepartment of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. 13111869074@163.com.

Funding

National Natural Science Foundation of China 82173903
6 · The paper itself

Abstract

Resveratrol is widely used in the fields of medicine and health supplements; however, its poor stability and low relative bioavailability limit its applications. This study aimed to compare the plasma drug concentrations and key pharmacokinetic parameters of two resveratrol solid formulations, T1 and T2. A single-center, randomized, open-label, two-formulation, single-dose, two-period, crossover trial was conducted involving 12 healthy subjects. Blood samples were collected after a single dose for pharmacokinetic (PK) analysis, including C

Indexed as

ResveratrolAdministration, OralAdultArea Under CurveBiological AvailabilityCross-Over StudiesFastingFemaleHealthy VolunteersHumansMaleYoung AdultResveratrolClinical trialsPharmacokineticsResveratrol

Identifiers

PMID40628835
PMCPMC12238501

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.