Evidence map›Paper›PMID 40628879›Full record

Trial reportScientific reports2025

Community interventions improve diabetes management and oral health in type 2 diabetes patients with chronic periodontitis.

Yi Zhang, Yijia Chen, Chenchen Wang, Hao Xu, Nan Zhou, Xin Hong

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi Zhang *Department of Chronic and Noncommunicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 16 Kunlun Road, Nanjing, 210000, China.
Yijia Chen *Department of Chronic and Noncommunicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 16 Kunlun Road, Nanjing, 210000, China.
Chenchen WangDepartment of Chronic and Noncommunicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 16 Kunlun Road, Nanjing, 210000, China.
Hao XuDepartment of Chronic and Noncommunicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 16 Kunlun Road, Nanjing, 210000, China.
Nan ZhouDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Xin HongDepartment of Chronic and Noncommunicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 16 Kunlun Road, Nanjing, 210000, China. nj_hongxin@126.com.

Funding

Nanjing Medical Science and Technology Development Project of China ZKX20045
6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) and chronic periodontitis are interrelated chronic conditions that exacerbate each other's progression. Despite their bidirectional relationship, oral health remains undervalued in diabetes management, particularly in underserved populations. The objective of this study was to assess whether a combined diabetes-periodontitis self-management intervention outperforms single-disease management in improving clinical outcomes, psychological well-being, and oral health in T2DM patients with chronic periodontitis. A randomized controlled trial was conducted across 12 community health centers in Nanjing, China, from June 2022 to June 2023. The participants (n = 784) were stratified into four groups, including G0 (control group, routine management), G1 (periodontal intervention), G2 (diabetes intervention), and G3 (comprehensive intervention), with 196 participants in each group. The control group (G0) received routine community-based diabetes management, while the intervention group (G1-G3) underwent a specialized self-management model-based intervention in addition to the routine management provided to the control group. The 3-month intervention included peer-led education on diabetes self-management, oral hygiene practices, dietary guidance, psychological support, and more. Outcomes [glycemic control, self-efficacy, quality of life (QoL), and oral health] were assessed at baseline (T0) and at 0 months (T1), 3 months (T2), and 6 months (T3) postintervention. Generalized estimating equations (GEEs) adjusted for covariates were used for longitudinal analysis. Compared with the other groups, the comprehensive intervention group (G3) had superior outcomes. At 3 months postintervention (T2), G3 showed the greatest improvements over G0 in terms of the fasting plasma glucose (FPG) control rate (B = 0.559, P = 0.027) and the glycated hemoglobin (HbA1c) control rate (B = 0.615, P = 0.007), alongside notable enhancements in self-efficacy (T1: B = 0.413, P = 0.020) and QoL (health utility: B = 0.025, P = 0.010). Specifically, compared with G0, G3 demonstrated marked improvements in oral health outcomes, including reduced gingival bleeding (B = - 0.751, P = 0.015), swelling (B = - 0.780, P = 0.018), tooth mobility (B= - 0.860, P = 0.007), chewing weakness (B = - 0.916, P = 0.015) and halitosis (B = - 0.763, P = 0.026). This study demonstrated that a community-based, integrated self-management intervention significantly improved glycemic control, self-efficacy, QoL, and oral health in T2DM patients with chronic periodontitis. By empowering patients through education and peer support, this model offers a scalable solution for underserved populations.

Indexed as

Chronic PeriodontitisDiabetes Mellitus, Type 2Oral HealthAdultAgedChinaFemaleHumansMaleMiddle AgedOral HygieneQuality of LifeSelf EfficacySelf-ManagementChronic periodontitisCommunity-based interventionGlycemic controlOral healthRandomized controlled trialType 2 diabetes mellitus

Identifiers

PMID40628879
PMCPMC12238377

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.